TREM1 抗体 (AA 21-200)
(1 reference)Quick Overview for TREM1 抗体 (AA 21-200) (ABIN5519068)
抗原
See all TREM1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 21-200
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原理
- Anti-TREM1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-TREM1 Antibody Picoband® (ABIN5519068). Tested in Flow Cytometry, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived human TREM1 recombinant protein (Position: A21-R200).
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亚型
- IgG
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anti-Triggering Receptor Expressed On Myeloid Cells 1 (TREM1) (AA 21-205) antibody
TREM1 适用: 人, 大鼠, 猴 WB, FACS, ELISA 宿主: 小鼠 Monoclonal 6B12D1 unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells 1 (TREM1) (AA 21-205) antibodyTREM1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells 1 (TREM1) (AA 21-205) antibodyTREM1 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 5F9F7 unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells 1 (TREM1) (AA 21-230) antibodyTREM1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells 1 (TREM1) (AA 21-234) antibodyTREM1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E2 unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells 1 (TREM1) (AA 74-90) antibodyTREM1 适用: 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells 1 (TREM1) (AA 21-234) antibodyTREM1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3F5 unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells 1 (TREM1) antibodyTREM1 适用: 人 WB, FACS, ELISA 宿主: 小鼠 Monoclonal TREM-37 unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells 1 (TREM1) antibodyTREM1 适用: 人 WB, FACS, ELISA 宿主: 小鼠 Monoclonal 6B1 unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells 1 (TREM1) antibody (PE)TREM1 适用: 人 FACS 宿主: 小鼠 Monoclonal 6B1 PE
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应用备注
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Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Frozen Section), 0.5-1 μg/mL
Immunocytochemistry, 0.5-1 μg/mL
Flow Cytometry (Fixed), 1-3 μg/1x106 cells
1. Allcock, R. J. N., Barrow, A. D., Forbes, S., Beck, S., Trowsdale, J.The human TREM gene cluster at 6p21.1 encodes both activating and inhibitory single IgV domain receptors and includes NKp44.Europ. J. Immun. 33: 567-577, 2003. 2. Bouchon, A., Dietrich, J., Colonna, M.Cutting edge: inflammatory responses can be triggered by TREM-1, a novel receptor expressed on neutrophils and monocytes.J. Immun. 164: 4991-4995, 2000. -
说明
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We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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: "Identification of Genes Associated with Smad3-dependent Renal Injury by RNA-seq-based Transcriptome Analysis." in: Scientific reports, Vol. 5, pp. 17901, (2016) (PubMed).
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: "Identification of Genes Associated with Smad3-dependent Renal Injury by RNA-seq-based Transcriptome Analysis." in: Scientific reports, Vol. 5, pp. 17901, (2016) (PubMed).
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- TREM1 (Triggering Receptor Expressed On Myeloid Cells 1 (TREM1))
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别名
- TREM1
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背景
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Synonyms: Triggering receptor expressed on myeloid cells 1, TREM-1, Triggering receptor expressed on monocytes 1, CD354, TREM1,
Tissue Specificity: Highly expressed in adult liver, lung and spleen than in corresponding fetal tissue. Also expressed in the lymph node, placenta, spinal cord and heart tissues. Expression is more elevated in peripheral blood leukocytes than in the bone marrow and in normal cells than malignant cells. Expressed at low levels in the early development of the hematopoietic system and in the promonocytic stage and at high levels in mature monocytes. Strongly expressed in acute inflammatory lesions caused by bacteria and fungi. Isoform 2 was detected in the lung, liver and mature monocytes.
Background: Trem1, Triggering receptor expressed on myeloid cells-1, is encoded by Trem1 gene. The expression of Trem1 is in monocytes and neutrophils but not in lymphocytes, dendritic cells, or other cell types. Trem1 is a 30-kD glycoprotein that is reduced to 26 kD by deglycosylation, in agreement with the predicted molecular mass. The Trem1 gene which contains 4 exons maps to chromosome 6p21.1, within a TREM gene cluster and the mouse Trem1 gene maps to chromosome 17 in a region that shows homology of synteny to human chromosome 6. The expression of Trem1 is upregulated by stimulation with lipopolysaccharide (LPS), gram-negative bacteria, and fungi. Cross-linking of Trem1 on neutrophils induces interleukin-8 (IL8) and myeloperoxidase secretion, while cross-linking on monocytes induces not only secretion of IL8 but also of monocyte chemotactic protein-1 (MCP1, or SCYA2) and tumor necrosis factor (TNF), MCP1 and TNF secretion could be further upregulated by LPS-mediated priming. Trem1 engagement also induces upregulation of adhesion molecules (e.g., ITGB1) and costimulatory molecules (e.g., CD40). Trem1 is associated with DAP12 (TYROBP), a molecule frequently associated with activating receptors.
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分子量
- 26 kDa
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基因ID
- 54210
抗原
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