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- 抗原 See all NOG 抗体
- NOG (Noggin (NOG))
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抗原表位
- AA 43-153
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NOG antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 原理
- Rabbit IgG polyclonal antibody for Noggin detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Noggin detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.
Gene Name: noggin
Protein Name: Noggin - 纯化方法
- Immunogen affinity purified.
- 免疫原
- E. coli-derived huamn Noggin recombinant protein (Position: L43-T153).
- 亚型
- IgG
- Top Product
- Discover our top product NOG Primary Antibody
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anti-Noggin (NOG) (AA 28-232) antibody
NOG 适用: 人, 犬 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 4C12 unconjugated
anti-Noggin (NOG) (AA 28-232) antibodyNOG 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal A7 unconjugated
anti-Noggin (NOG) (AA 28-232) antibodyNOG 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Noggin (NOG) (AA 1-232) antibodyNOG 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Noggin (NOG) (AA 28-130) antibodyNOG 适用: 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Noggin (NOG) (AA 28-232) antibodyNOG 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Noggin (NOG) antibodyNOG 适用: 人, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Noggin (NOG) (AA 21-70) antibodyNOG 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Noggin (NOG) antibodyNOG 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Noggin (NOG) (AA 1-232) antibodyNOG 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
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Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- NOG (Noggin (NOG))
- 别名
- NOG (NOG 产品)
- 别名
- SYM1 antibody, SYNS1 antibody, nog-A antibody, nog1 antibody, noggin-1 antibody, noggin antibody, noggin antibody, noggin L homeolog antibody, noggin protein antibody, NOG antibody, Nog antibody, nog.L antibody, noggin antibody
- 背景
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The secreted polypeptide, encoded by NOG gene, binds and inactivates members of the transforming growth factor-beta (TGF-beta) superfamily signaling proteins, such as bone morphogenetic protein-4 (BMP4). By diffusing through extracellular matrices more efficiently than members of the TGF-beta superfamily, this protein may have a principal role in creating morphogenic gradients. The protein appears to have pleiotropic effect, both early in development as well as in later stages. It was originally isolated from Xenopus based on its ability to restore normal dorsal-ventral body axis in embryos that had been artificially ventralized by UV treatment. The results of the mouse knockout of the ortholog suggest that it is involved in numerous developmental processes, such as neural tube fusion and joint formation. Recently, several dominant human NOG mutations in unrelated families with proximal symphalangism (SYM1) and multiple synostoses syndrome (SYNS1) were identified, both SYM1 and SYNS1 have multiple joint fusion as their principal feature, and map to the same region (17q22) as this gene. All of these mutations altered evolutionarily conserved amino acid residues. The amino acid sequence of this human gene is highly homologous to that of Xenopus, rat and mouse.
Synonyms: Noggin, NOG - 基因ID
- 9241
- UniProt
- Q13253
- 途径
- Stem Cell Maintenance, Tube Formation
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