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NOG 抗体 (AA 43-153)

This anti-NOG antibody is a 兔多克隆 antibody detecting NOG in WB, IHC 和 ELISA. Suitable for 人.

Western blot analysis of Noggin using anti-Noggin antibody . (NOG 抗体 (AA 43-153))

1 image

产品编号 ABIN5519047

发货至: 中国

Quick Overview for NOG 抗体 (AA 43-153) (ABIN5519047)

抗原

See all NOG 抗体

NOG (Noggin (NOG))

适用

67
46
32
9
8
7
1
1
1

人

宿主

兔

克隆类型

多克隆

标记

57
21
7
4
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1

This NOG antibody is un-conjugated

应用范围

95
51
37
28
26
14
13
13
6
6
5
3
1

Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Discover our top product NOG Primary Antibody

抗原表位
26

16

7

4

3

3

3

3

2

2

2

2

1

1

1

1

1

1
AA 43-153

原理

Anti-Noggin Antibody Picoband®

交叉反应（详细）

No cross-reactivity with other proteins.

产品特性

Anti-Noggin Antibody Picoband® (ABIN5519047). Tested in ELISA, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

E. coli-derived human Noggin recombinant protein (Position: L43-T153).

亚型

IgG
anti-Noggin (NOG) (AA 28-232) antibody
NOG 适用: 人, 犬 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 4C12 unconjugated

anti-Noggin (NOG) (AA 28-232) antibody
NOG 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal A7 unconjugated

anti-Noggin (NOG) (AA 28-232) antibody
NOG 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Noggin (NOG) (AA 1-232) antibody
NOG 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-Noggin (NOG) (AA 28-130) antibody
NOG 适用: 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Noggin (NOG) (AA 28-232) antibody
NOG 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Noggin (NOG) antibody
NOG 适用: 人, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Noggin (NOG) (AA 21-70) antibody
NOG 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Noggin (NOG) (AA 28-232) antibody
NOG 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4C9 unconjugated

anti-Noggin (NOG) (AA 1-232) antibody
NOG 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
ELISA, 0.1-0.5 μg/mL
1. Marcelino J, Sciortino CM, Romero MF, Ulatowski LM, Ballock RT, Economides AN, Eimon PM, Harland RM, Warman ML (Sep 2001). "Human disease-causing NOG missense mutations: effects on noggin secretion, dimer formation, and bone morphogenetic protein binding". Proceedings of the National Academy of Sciences of the United States of America. 98 (20): 11353-8. 2. Oppenheimer SB (1995). "The Discovery of Noggin". The American Biology Teacher. 57 (5): 264.

说明

We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.01 mg NaN₃.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
抗原

NOG (Noggin (NOG))

别名

NOG

背景

Synonyms: Noggin, NOG,
Tissue Specificity: Expressed at low levels in several tissues, including brain, kidney, lung, prostate, testis, spinal cord, adrenal gland, and trachea.
Background: The secreted polypeptide, encoded by NOG gene, binds and inactivates members of the transforming growth factor-beta (TGF-beta) superfamily signaling proteins, such as bone morphogenetic protein-4 (BMP4). By diffusing through extracellular matrices more efficiently than members of the TGF-beta superfamily, this protein may have a principal role in creating morphogenic gradients. The protein appears to have pleiotropic effect, both early in development as well as in later stages. It was originally isolated from Xenopus based on its ability to restore normal dorsal-ventral body axis in embryos that had been artificially ventralized by UV treatment. The results of the mouse knockout of the ortholog suggest that it is involved in numerous developmental processes, such as neural tube fusion and joint formation. Recently, several dominant human NOG mutations in unrelated families with proximal symphalangism (SYM1) and multiple synostoses syndrome (SYNS1) were identified, both SYM1 and SYNS1 have multiple joint fusion as their principal feature, and map to the same region (17q22) as this gene. All of these mutations altered evolutionarily conserved amino acid residues. The amino acid sequence of this human gene is highly homologous to that of Xenopus, rat and mouse.

分子量

26 kDa

基因ID

9241

途径

Stem Cell Maintenance, Tube Formation

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