KIT Ligand 抗体 (AA 26-190)
(3 references)Quick Overview for KIT Ligand 抗体 (AA 26-190) (ABIN5519022)
抗原
See all KIT Ligand (KITLG) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 26-190
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原理
- Anti-SCF/KITLG Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-SCF/KITLG Antibody Picoband® (ABIN5519022). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived human SCF recombinant protein (Position: E26-A190).
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亚型
- IgG
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anti-KIT Ligand (KITLG) (AA 151-250) antibody
KITLG 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-KIT Ligand (KITLG) antibodyKITLG 适用: 人 WB, ELISA, Neut 宿主: 兔 Polyclonal unconjugated
anti-KIT Ligand (KITLG) (AA 244-273) antibodyKITLG 适用: 人 WB, ELISA, FACS, IF 宿主: 兔 Polyclonal unconjugated
anti-KIT Ligand (KITLG) (Middle Region) antibodyKITLG 适用: 人, 小鼠, 大鼠, Pig, 犬, Cow, 山羊, 马, 兔, 绵羊, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-KIT Ligand (KITLG) (AA 180-229) antibodyKITLG 适用: 人, 小鼠, 大鼠, Pig, 犬, Cow, 山羊, 马, 兔, 绵羊, 小鸡, Hamster, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-KIT Ligand (KITLG) (Middle Region) antibodyKITLG 适用: 人, 小鼠, 大鼠, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-KIT Ligand (KITLG) antibodyKITLG 适用: 人, 小鼠, 大鼠 WB, IHC (p), ELISA (Capture) 宿主: 兔 Polyclonal unconjugated
anti-KIT Ligand (KITLG) (AA 201-234), (C-Term) antibodyKITLG 适用: 人 WB 宿主: 兔 Polyclonal RB50736 unconjugated
anti-KIT Ligand (KITLG) antibody (Biotin)KITLG 适用: 小鼠 WB, ELISA, Neut 宿主: 兔 Polyclonal Biotin
anti-KIT Ligand (KITLG) antibody (Biotin)KITLG 适用: 人 WB, ELISA, Neut 宿主: 兔 Polyclonal Biotin
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应用备注
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Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
1. Geissler, E. N., Liao, M., Brook, J. D., Martin, F. H., Zsebo, K. M., Housman, D. E., Galli, S. J.Stem cell factor (SCF), a novel hematopoietic growth factor and ligand for c-kit tyrosine kinase receptor, maps on human chromosome 12 between 12q14.3 and 12qter.Somat. Cell Molec. Genet. 17: 207-214, 1991. 2. Heissig, B., Hattori, K., Dias, S., Friedrich, M., Ferris, B., Hackett, N. R., Crystal, R. G., Besmer, P., Lyden, D., Moore, M. A. S., Werb, Z., Rafii, S.Recruitment of stem and progenitor cells from the bone marrow niche requires MMP-9 mediated release of Kit-ligand.Cell 109: 625-637, 2002. -
说明
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We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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: "Effects of Polysaccharide of Gastrodia Elata Blume and Electro-Acupuncture on Expressions of Brain-Derived Neurotrophic Factor and Stem Cell Factor Protein in Caudate Putamen of Focal Cerebral ..." in: Medical science monitor basic research, Vol. 22, pp. 175-180, (2017) (PubMed).
: "Tropism of liver epithelial cells toward hepatocellular carcinoma in vitro and in vivo with altering gene expression of cancer stem cells." in: American journal of surgery, Vol. 215, Issue 4, pp. 735-743, (2017) (PubMed).
: "Selective tropism of liver stem cells to hepatocellular carcinoma in vivo." in: World journal of gastroenterology, Vol. 13, Issue 28, pp. 3886-91, (2007) (PubMed).
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: "Effects of Polysaccharide of Gastrodia Elata Blume and Electro-Acupuncture on Expressions of Brain-Derived Neurotrophic Factor and Stem Cell Factor Protein in Caudate Putamen of Focal Cerebral ..." in: Medical science monitor basic research, Vol. 22, pp. 175-180, (2017) (PubMed).
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- KIT Ligand (KITLG)
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别名
- KITLG
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背景
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Synonyms: Kit ligand, Mast cell growth factor, MGF, Stem cell factor, SCF, c-Kit ligand, Soluble KIT ligand, sKITLG, KITLG, MGF, SCF,
Background: Stem Cell Factor (also known as SCF, kit-ligand, KL, or steel factor) is a cytokine that binds to the c-Kit receptor (CD117). The SCF gene is mapped to 12q21.32. SCF can exist both as a transmembrane protein and a soluble protein. This cytokine plays an important role in hematopoiesis (formation of blood cells), spermatogenesis, and melanogenesis. SCF may be used along with other cytokines to culture HSCs and hematopoietic progenitors. The expansion of these cells ex-vivo (outside the body) would allow advances in bone-marrow transplantation, in which HSCs are transferred to a patient to re-establish blood formation. One of the problems of injecting SCF for therapeutic purposes is that SCF activates mast cells. The injection of SCF has been shown to cause allergic-like symptoms and the proliferation of mast cells and melanocytes.
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分子量
- 37 kDa
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基因ID
- 4254
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
抗原
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