FLT4 抗体
(1 reference)Quick Overview for FLT4 抗体 (ABIN5518991)
抗原
See all FLT4 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Anti-VEGF Receptor 3/FLT4 Antibody Picoband®
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序列
- SCRGQHPLEW AWPGAQEAPA TGDKDSEDT
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-VEGF Receptor 3/FLT4 Antibody Picoband® (ABIN5518991). Tested in Flow Cytometry, IF, IHC, IHC-F, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human VEGF Receptor 3, which shares 82.8% and 79.3% amino acid (aa) sequence identity with mouse and rat VEGF Receptor 3, respectively.
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亚型
- IgG
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anti-Fms-Related Tyrosine Kinase 4 (FLT4) (AA 25-259) antibody
FLT4 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, FACS, ICC, IF, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fms-Related Tyrosine Kinase 4 (FLT4) (AA 1174-1363) antibodyFLT4 适用: 人 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fms-Related Tyrosine Kinase 4 (FLT4) (AA 1-439) antibodyFLT4 适用: 人 WB, FACS, IHC (p) 宿主: 小鼠 Monoclonal 818CT12-1-1 unconjugated
anti-Fms-Related Tyrosine Kinase 4 (FLT4) antibodyFLT4 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 818CT12-1-1 unconjugated
anti-Fms-Related Tyrosine Kinase 4 (FLT4) (AA 901-1000) antibodyFLT4 适用: 人, 小鼠, Cow ELISA, FACS, ICC, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fms-Related Tyrosine Kinase 4 (FLT4) (AA 720-760) antibodyFLT4 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Fms-Related Tyrosine Kinase 4 (FLT4) (AA 34-133) antibodyFLT4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5B5 unconjugated
anti-Fms-Related Tyrosine Kinase 4 (FLT4) antibodyFLT4 适用: 人 IHC (p) 宿主: 小鼠 Monoclonal 8C1 unconjugated
anti-Fms-Related Tyrosine Kinase 4 (FLT4) (AA 640-700) antibodyFLT4 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Fms-Related Tyrosine Kinase 4 (FLT4) (AA 1112-1329) antibodyFLT4 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
Immunohistochemistry (Frozen Section), 0.5-1 μg/mL
Immunocytochemistry/Immunofluorescence, 2 μg/mL
Flow Cytometry (Fixed), 1-3 μg/1x106 cells1. Aprelikova, O., Pajusola, K., Partanen, J., Armstrong, E., Alitalo, R., Bailey, S. K., McMahon, J., Wasmuth, J., Huebner, K., Alitalo, K. FLT4, a novel class III receptor tyrosine kinase in chromosome 5q33-qter. Cancer Res. 52: 746-748, 1992. 2. Galland, F., Karamysheva, A., Mattei, M.-G., Rosnet, O., Marchetto, S., Birnbaum, D. Chromosomal localization of FLT4, a novel receptor-type tyrosine kinase gene. Genomics 13: 475-478, 1992. -
说明
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We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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: "Expression of angiopoietin-2 and vascular endothelial growth factor receptor-3 correlates with lymphangiogenesis and angiogenesis and affects survival of oral squamous cell carcinoma." in: PLoS ONE, Vol. 8, Issue 9, pp. e75388, (2013) (PubMed).
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: "Expression of angiopoietin-2 and vascular endothelial growth factor receptor-3 correlates with lymphangiogenesis and angiogenesis and affects survival of oral squamous cell carcinoma." in: PLoS ONE, Vol. 8, Issue 9, pp. e75388, (2013) (PubMed).
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- FLT4 (Fms-Related Tyrosine Kinase 4 (FLT4))
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别名
- FLT4
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背景
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Synonyms: Vascular endothelial growth factor receptor 3, VEGFR-3, 2.7.10.1, Fms-like tyrosine kinase 4, FLT-4, Tyrosine-protein kinase receptor FLT4, FLT4, VEGFR3,
Tissue Specificity: Detected in endothelial cells (at protein level). Widely expressed. Detected in fetal spleen, lung and brain. Detected in adult liver, muscle, thymus, placenta, lung, testis, ovary, prostate, heart, and kidney.
Background: Fms-related tyrosine kinase 4, also known as FLT4 or VEGFR3, is a protein which in humans is encoded by the FLT4 gene. It is mapped to 5q35.3. This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. FLT4 has an essential role in the development of the embryonic cardiovascular system before the emergence of the lymphatic vessels. It has been found that FLT4, which provides proangiogenic signaling when expressed on endothelium, may also have antiangiogenic properties when expressed at an avascular site by nonendothelial cells. FLT4 is also regarded as a regulator of vascular network formation.
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分子量
- 153 kDa
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基因ID
- 2324
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UniProt
- P35916
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途径
- RTK signaling, Signaling Events mediated by VEGFR1 and VEGFR2, VEGF Signaling
抗原
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