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FGF8 抗体 (AA 23-233)

FGF8 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5518985
发货至: 中国
  • 抗原 See all FGF8 抗体
    FGF8 (Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8))
    抗原表位
    • 15
    • 13
    • 8
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 23-233
    适用
    • 44
    • 31
    • 25
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 54
    • 5
    • 1
    克隆类型
    • 55
    • 5
    多克隆
    标记
    • 24
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FGF8 antibody is un-conjugated
    应用范围
    • 45
    • 27
    • 13
    • 13
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    原理
    Rabbit IgG polyclonal antibody for FGF8 detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for FGF8 detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.
    Gene Name: fibroblast growth factor 8
    Protein Name: Fibroblast growth factor 8
    纯化方法
    Immunogen affinity purified.
    免疫原
    E. coli-derived human FGF8 recombinant protein (Position: Q23-R233).
    亚型
    IgG
    Top Product
    Discover our top product FGF8 Primary Antibody
  • 应用备注
    Notes: Tested Species: Species with positive results.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Boster recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • 抗原
    FGF8 (Fibroblast Growth Factor 8 (Androgen-Induced) (FGF8))
    别名
    FGF8 (FGF8 产品)
    别名
    Aigf antibody, Fgf-8 antibody, AIGF antibody, FGF-8 antibody, HBGF-8 antibody, HH6 antibody, KAL6 antibody, fibroblast growth factor 8 antibody, Fgf8 antibody, FGF8 antibody
    背景
    Fibroblast growth factor 8 (androgen-induced), also known as FGF8 or AIGF, is a human gene which maps to 10q24. The protein encoded by this gene is secreted proteins that interact with FGF tyrosine kinase receptors to mediate growth and development. This protein is known to be a factor that supports androgen and anchorage independent growth of mammary tumor cells. Overexpression of this gene has been shown to increase tumor growth and angiogensis. The temporal and spatial patterns of this gene expression suggest that FGF8 is involved in gastrulation, regionalization of the brain, and organogenesis of the limb and face as an embryonic epithelial factor. The adult expression of FGF8 is restricted to gonads, including testes and ovaries. FGF8 stimulated growth of human prostate carcinoma cells and mouse fibroblasts and mammary carcinoma cells in a dose-dependent manner. It also may play an important role in growth and patterning of limbs, face, and central nervous system. FGF8 is expressed in increased levels in breast cancer and in lactating human breast, it was also detected in human milk. A survey of other normal tissues showed that FGF8 is expressed in the proliferative cells of the skin and epithelial cells in colon, ovary, fallopian tube, and uterus.

    Synonyms: Fibroblast growth factor 8, FGF-8, Androgen-induced growth factor, AIGF, Heparin-binding growth factor 8, HBGF-8, FGF8, AIGF
    基因ID
    2253
    UniProt
    P55075
    途径
    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Dopaminergic Neurogenesis
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