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FGF7 抗体 (AA 32-194)

FGF7 适用: 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5518984
发货至: 中国
  • 抗原 See all FGF7 抗体
    FGF7 (Fibroblast Growth Factor 7 (FGF7))
    抗原表位
    • 14
    • 6
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    AA 32-194
    适用
    • 44
    • 27
    • 26
    • 14
    小鼠, 大鼠
    宿主
    • 60
    • 2
    克隆类型
    • 57
    • 5
    多克隆
    标记
    • 22
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FGF7 antibody is un-conjugated
    应用范围
    • 47
    • 26
    • 12
    • 12
    • 11
    • 7
    • 7
    • 6
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    原理
    Anti-KGF/Fgf7 Antibody Picoband®
    交叉反应 (详细)
    No cross-reactivity with other proteins.
    产品特性
    Anti-KGF/Fgf7 Antibody Picoband® (ABIN5518984). Tested in ELISA, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    纯化方法
    Immunogen affinity purified.
    免疫原
    E. coli-derived mouse KGF recombinant protein (Position: C32-T194).
    亚型
    IgG
    Top Product
    Discover our top product FGF7 Primary Antibody
  • 应用备注
    Western blot, 0.1-0.5 μg/mL
    ELISA, 0.1-0.5 μg/mL
    1. Kelley MJ, Pech M, Seuanez HN, Rubin JS, O'Brien SJ, Aaronson SA (Nov 1992). "Emergence of the keratinocyte growth factor multigene family during the great ape radiation". Proc Natl Acad Sci U S A 89 (19): 9287-91. 2. Mattei MG, deLapeyriere O, Bresnick J, Dickson C, Birnbaum D, Mason I (Jun 1995). "Mouse Fgf7 (fibroblast growth factor 7) and Fgf8 (fibroblast growth factor 8) genes map to chromosomes 2 and 19 respectively". Mamm Genome 6 (3): 196-7.
    说明

    We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Li, Liang, Zhao, Uchida, Baba, Huang, Bai, Bai, Zhang: "The effects of adenoviral transfection of the keratinocyte growth factor gene on epidermal stem cells: an in vitro study." in: Molecules and cells, Vol. 36, Issue 4, pp. 316-21, (2013) (PubMed).

  • 抗原
    FGF7 (Fibroblast Growth Factor 7 (FGF7))
    别名
    Fgf7 (FGF7 产品)
    背景

    Synonyms: Fibroblast growth factor 7, FGF-7, Heparin-binding growth factor 7, HBGF-7, Keratinocyte growth factor, KGF, Fgf7, Fgf-7, Kgf,

    Tissue Specificity: Ubiquitous. Expressed in the rod and cone photoreceptors, extending from the tips of the outer segment (OS) through the inner segment (IS) and outer nuclear layer (ONL) and into the synaptic terminals of the outer plexiform layer (ONL). Also detected in the bipolar, horizontal and amacrine cells in the inner nuclear layer (INL), extending to the inner plexiform layer (IPL) and though the ganglion cell layer (GCL) and into the nerve fiber layer (NFL) (at protein level).

    Background: Keratinocyte growth factor is a protein that in humans is encoded by the FGF7 gene. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. Studies of mouse and rat homologs of this gene implicated roles in morphogenesis of epithelium, reepithelialization of wounds, hair development and early lung organogenesis.

    分子量
    22 kDa
    基因ID
    14178
    UniProt
    P36363
    途径
    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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