CCL20 抗体 (AA 28-97)
Quick Overview for CCL20 抗体 (AA 28-97) (ABIN5518973)
抗原
See all CCL20 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 28-97
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原理
- Anti-MIP-3 Alpha/CCL20 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-MIP-3 Alpha/CCL20 Antibody Picoband® (ABIN5518973). Tested in ELISA, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived mouse MIP-3 Alpha/CCL20 recombinant protein (Position: A28-M97).
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亚型
- IgG
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anti-Chemokine (C-C Motif) Ligand 20 (CCL20) antibody (PE)
CCL20 适用: 人 FACS 宿主: 小鼠 Monoclonal UCHL1 PE
anti-Chemokine (C-C Motif) Ligand 20 (CCL20) antibodyCCL20 适用: 人 IP, FACS, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal UCHL1 unconjugated
anti-Chemokine (C-C Motif) Ligand 20 (CCL20) (AA 24-97) antibodyCCL20 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 20 (CCL20) (AA 27-96) antibodyCCL20 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal A4 unconjugated
anti-Chemokine (C-C Motif) Ligand 20 (CCL20) antibody (FITC)CCL20 适用: 人 FACS 宿主: 小鼠 Monoclonal UCHL1 FITC
anti-Chemokine (C-C Motif) Ligand 20 (CCL20) (AA 31-97) antibodyCCL20 适用: 人, 小鼠 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 20 (CCL20) (AA 24-95) antibodyCCL20 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Chemokine (C-C Motif) Ligand 20 (CCL20) (Internal Region) antibodyCCL20 适用: 人, 小鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 20 (CCL20) antibody (APC)CCL20 适用: 人 FACS 宿主: 小鼠 Monoclonal UCHL1 APC
anti-Chemokine (C-C Motif) Ligand 20 (CCL20) (AA 24-95) antibodyCCL20 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL
ELISA (Cap), 1-5 μg/mL
1. Harant, H., Eldershaw, S. A, Lindley, I. J. Human macrophage inflammatory protein-3-alpha/CCL20/LARC/EXODUS/SCYA20 is transcriptionally upregulated by tumor necrosis factor-alpha via a non-standard NF-kappa-B site. FEBS Lett. 509: 439-445, 2001. 2. Nelson, R. T., Boyd, J., Gladue, R. P., Paradis, T., Thomas, R., Cunningham, A. C., Lira, P., Brissette, W. H., Hayes, L., Hames, L. M., Neote, K. S., McColl, S. R. Genomic organization of the CC chemokine MIP-3-alpha/CCL20/LARC/EXODUS/SCYA20, showing gene structure, splice variants, and chromosome localization. Genomics 73: 28-37, 2001. -
说明
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We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- CCL20 (Chemokine (C-C Motif) Ligand 20 (CCL20))
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别名
- Ccl20
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背景
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Synonyms: C-C motif chemokine 20, Beta-chemokine exodus-1, CC chemokine LARC, CC chemokine ST38, Liver and activation-regulated chemokine, Macrophage inflammatory protein 3 alpha, MIP-3-alpha, Small-inducible cytokine A20, Ccl20, Larc, Scya20,
Tissue Specificity: Thymic medulla (at protein level). Prominently expressed in the small intestine, colon and appendix. Also found in thymus, spleen, lymph node and lung. The long form might be dominant in intestinal, and the short form in lymphoid tissues. Expressed by IL17 producing helper T-cells (Th17).
Background: Macrophage Inflammatory Protein 3alpha (MIP3alpha), also called Chemokine, cc motif, ligand 20 (CCL20). The MIP-3alpha/CCL20 gene was cloned and sequenced, revealing a four exon, three intron structure, and was localized by FISH analysis to 2q35-q36. MIP3alpha is predominantly expressed in lymph nodes, appendix, PBL, fetal liver, fetal lung and several cell lines. MIP3alpha/CCL20 and its receptor CCR6 are markedly up-regulated in psoriasis, and they may play a role in the recruitment of T cells to lesional psoriatic skin. And Alanine MIP-3alpha and Serine MIP-3alpha, the two forms of MIP3alpha, that differ by one amino acid at the predicted signal peptide cleavage site. Both of them were chemically synthesized and tested for biological activity. And both flu antigen plus IL-2-activated CD4 (+) and CD8 (+) T lymphoblasts and cord blood-derived dendritic cells responded to Ser and Ala MIP-3alpha.
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分子量
- 14 kDa
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基因ID
- 20297
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UniProt
- O89093
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途径
- The Global Phosphorylation Landscape of SARS-CoV-2 Infection
抗原
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