VSX2 抗体 (AA 249-361)
Quick Overview for VSX2 抗体 (AA 249-361) (ABIN5518966)
抗原
See all VSX2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 249-361
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原理
- Anti-CHX10/VSX2 Antibody Picoband®
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-CHX10/VSX2 Antibody Picoband® (ABIN5518966). Tested in WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived human CHX10 recombinant protein (Position: A249-A361). Human CHX10 shares 90.3% amino acid (aa) sequence identity with mouse CHX10.
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亚型
- IgG
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应用备注
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Western blot, 0.1-0.5 μg/mL, Mouse, Human
1. McInnes, R. R., Basu, S., Novak, J., Ploder, L., Liang, M.-Y., Hawes, N., Taylor, B., Roderick, T., Goldman, D., Hankin, M., Burmeister, M. The ocular retardation (orJ) mouse has an ochre mutation in the homeobox gene Chx10: evidence for Chx10 as a major determinant of retinal development. (Abstract) Am. J. Hum. Genet. 55 (suppl.): A3, 1994. 2. Reichman, S., Kalathur, R. K. R., Lambard, S., Ait-Ali, N., Yang, Y., Lardenois, A., Ripp, R., Poch, O., Zack, D. J., Sahel, J.-A., Leveillard, T. The homeobox gene CHX10/VSX2 regulates RdCVF promoter activity in the inner retina. Hum. Molec. Genet. 19: 250-261, 2010. -
说明
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We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- VSX2 (Visual System Homeobox 2 (VSX2))
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别名
- VSX2
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背景
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Synonyms: Visual system homeobox 2,Ceh-10 homeodomain-containing homolog,Homeobox protein CHX10,VSX2,CHX10, HOX10,
Tissue Specificity: Abundantly expressed in retinal neuroblasts during eye development and in the inner nuclear layer of the adult retina. Within this layer, expression is stronger in the outer margin where bipolar cells predominate.
Background: Visual system homeobox 2 is a protein that in humans is encoded by the VSX2 gene. This gene encodes a homeobox protein originally described as a retina-specific transcription factor. Mutations in this gene are associated with microphthalmia, cataracts and iris abnormalities. In situ hybridization to human fetal retinal sections detected CHX10 expression in retinal neuroblasts at all stages examined. Human CHX10 is expressed in progenitor cells of the developing neuroretina and in the inner nuclear layer of the mature retina.
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分子量
- 43 kDa
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基因ID
- 338917
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UniProt
- P58304
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途径
- Dopaminergic Neurogenesis
抗原
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