UCP2 抗体 (Middle Region)
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北京 101111
Quick Overview for UCP2 抗体 (Middle Region) (ABIN5518965)
抗原
See all UCP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- Anti-UCP2 Antibody
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序列
- AQPTDVVKVR FQAQARAGGG RRYQSTVNAY KTIAREE
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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预测反应
- different from the related mouse,rat sequences by one amino acid.
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产品特性
- Anti-UCP2 Antibody. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human UCP2, different from the related mouse and rat sequences by one amino acid.
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亚型
- IgG
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anti-Uncoupling Protein 2 (Mitochondrial, Proton Carrier) (UCP2) (Internal Region) antibody
Verified UCP2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Uncoupling Protein 2 (Mitochondrial, Proton Carrier) (UCP2) (AA 154-289) antibodyUCP2 适用: 人 IHC 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Uncoupling Protein 2 (Mitochondrial, Proton Carrier) (UCP2) (AA 99-216) antibodyUCP2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Uncoupling Protein 2 (Mitochondrial, Proton Carrier) (UCP2) (AA 1-309) antibodyUCP2 适用: 人 ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 3F1B9 unconjugated
anti-Uncoupling Protein 2 (Mitochondrial, Proton Carrier) (UCP2) (AA 154-289) antibodyUCP2 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal D7 unconjugated
anti-Uncoupling Protein 2 (Mitochondrial, Proton Carrier) (UCP2) (AA 201-309) antibodyUCP2 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), FACS, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Uncoupling Protein 2 (Mitochondrial, Proton Carrier) (UCP2) (AA 1-309) antibodyUCP2 适用: 人 ELISA 宿主: 小鼠 Monoclonal 6C8B3 unconjugated
anti-Uncoupling Protein 2 (Mitochondrial, Proton Carrier) (UCP2) (AA 153-164), (Intracellular) antibodyUCP2 适用: 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Uncoupling Protein 2 (Mitochondrial, Proton Carrier) (UCP2) (AA 150-304) antibodyUCP2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Uncoupling Protein 2 (Mitochondrial, Proton Carrier) (UCP2) (AA 154-289) antibodyUCP2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
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说明
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We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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: "Exhaustive training increases uncoupling protein 2 expression and decreases Bcl-2/Bax ratio in rat skeletal muscle." in: Oxidative medicine and cellular longevity, Vol. 2013, pp. 780719, (2013) (PubMed).
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- UCP2 (Uncoupling Protein 2 (Mitochondrial, Proton Carrier) (UCP2))
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别名
- UCP2
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背景
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Background: Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed in many tissues, with the greatest expression in skeletal muscle. It is thought to play a role in nonshivering thermogenesis, obesity and diabetes. Chromosomal order is 5'-UCP3-UCP2-3'.
Gene Full Name: uncoupling protein 2
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分子量
- 33 kDa
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基因ID
- 7351
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UniProt
- P55851
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途径
- Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Proton Transport
抗原
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