TFF1 抗体 (AA 22-87)
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北京 101111
Quick Overview for TFF1 抗体 (AA 22-87) (ABIN5518960)
抗原
See all TFF1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 22-87
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原理
- Anti-Estrogen Inducible Protein pS2/Tff1 Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Estrogen Inducible Protein pS2/Tff1 Antibody (ABIN5518960). Tested in ELISA, IHC, WB applications. This antibody reacts with Mouse. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived mouse Tff1 recombinant protein (Position: Q22-F87). Mouse Tff1 shares 67.2% and 83.6% amino acid (aa) sequence identity with human and rat Tff1, respectively.
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亚型
- IgG
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anti-Trefoil Factor 1 (TFF1) antibody
TFF1 适用: 人 IHC, IF, FACS, StM 宿主: 小鼠 Monoclonal TFF1-2133 unconjugated
anti-Trefoil Factor 1 (TFF1) (AA 25-84), (pSer2) antibodyTFF1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Trefoil Factor 1 (TFF1) antibodyTFF1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Trefoil Factor 1 (TFF1) (AA 1-87) antibodyTFF1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Trefoil Factor 1 (TFF1) (AA 1-81) antibodyTFF1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Trefoil Factor 1 (TFF1) (AA 1-88) antibodyTFF1 适用: 人 IHC 宿主: 小鼠 Monoclonal 482M unconjugated
anti-Trefoil Factor 1 (TFF1) (AA 1-84) antibodyTFF1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3H5 unconjugated
anti-Trefoil Factor 1 (TFF1) (AA 57-84) antibodyTFF1 适用: 人, Cynomolgus IHC, StM 宿主: 小鼠 Monoclonal GE2-same as R47-94 unconjugated
anti-Trefoil Factor 1 (TFF1) (AA 1-84) antibodyTFF1 适用: 人 WB, IHC, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Trefoil Factor 1 (TFF1) (AA 25-84) antibodyTFF1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Mouse
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Mouse
ELISA(Cap), 1-5 μg/mL, Mouse
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说明
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We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- TFF1 (Trefoil Factor 1 (TFF1))
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别名
- Tff1
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背景
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Synonyms: Trefoil factor 1,Protein pS2,Tff1,Bcei, Ps2,
Tissue Specificity: Strong expression found in normal gastric mucosa. Not detected in the small or large intestine nor in normal mammary gland.
Background: TFF1 (Trefoil factor 1), also known as pS2, is a protein that in humans is encoded by the TFF1 gene. Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. It is found that TFF1 in normal human urine inhibited the growth of calcium oxalate crystals. Urinary TFF1 showed an inhibitory potency similar to that of nephrocalcin, and inhibition was dose dependent and inhibited by TFF1 antisera, particularly by antisera ed to the TFF1 C terminus. Concentrations and relative amounts of TFF1 in the urine of patients with idiopathic calcium oxalate kidney stones were significantly less than those found in controls. This gene, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21.
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分子量
- 17 kDa
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基因ID
- 21784
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UniProt
- Q08423
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途径
- EGFR Signaling Pathway
抗原
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