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SIX3 抗体 (N-Term)

This anti-SIX3 antibody is a 兔多克隆 antibody detecting SIX3 in WB. Suitable for 人, 小鼠和大鼠.

Western blot analysis of Six3 using anti-Six3 antibody . (SIX3 抗体 (N-Term))

1 image

产品编号 ABIN5518955

发货至: 中国

Quick Overview for SIX3 抗体 (N-Term) (ABIN5518955)

抗原

See all SIX3 抗体

SIX3 (Sine Oculis-Related Homeobox 3 (SIX3))

适用

35
12
8
3
3
2
2
2
1

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

22
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1

This SIX3 antibody is un-conjugated

应用范围

40
18
13
13
5
4
3
3
3
2
1
1

Western Blotting (WB)

Discover our top product SIX3 Primary Antibody

抗原表位
15

8

6

3

3

2

2

2

1

1

1

1
AA 1-32, N-Term

原理

Anti-Six3 Antibody

序列

MVFRSPLDLY SSHFLLPNFA DSHHRSILLA SS

交叉反应（详细）

No cross-reactivity with other proteins.

产品特性

Anti-Six3 Antibody (ABIN5518955). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence at the N-terminus of human Six3, different from the related mouse sequence by two amino acids.

亚型

IgG
anti-Sine Oculis-Related Homeobox 3 (SIX3) (AA 273-332) antibody
SIX3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4H6 unconjugated

anti-Sine Oculis-Related Homeobox 3 (SIX3) (Internal Region) antibody
SIX3 适用: 小鼠 WB, ELISA, IHC, IF, FM, DB 宿主: 豚鼠 Polyclonal unconjugated

anti-Sine Oculis-Related Homeobox 3 (SIX3) (AA 273-332) antibody
SIX3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3D12 unconjugated

anti-Sine Oculis-Related Homeobox 3 (SIX3) (Internal Region) antibody
SIX3 适用: 小鼠 WB, ELISA, IHC, IF, FM, DB 宿主: 豚鼠 Polyclonal unconjugated

anti-Sine Oculis-Related Homeobox 3 (SIX3) (C-Term) antibody
SIX3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Sine Oculis-Related Homeobox 3 (SIX3) (Internal Region) antibody
SIX3 适用: 小鼠 WB, ELISA, IHC, FM 宿主: 兔 Polyclonal unconjugated

anti-Sine Oculis-Related Homeobox 3 (SIX3) (Internal Region) antibody
SIX3 适用: 小鼠 WB, ELISA, IHC, FM 宿主: 兔 Polyclonal unconjugated

anti-Sine Oculis-Related Homeobox 3 (SIX3) (AA 1-332) antibody
SIX3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated

anti-Sine Oculis-Related Homeobox 3 (SIX3) (N-Term) antibody
SIX3 适用: 人, 小鼠, 大鼠, 犬, 猴 WB 宿主: 兔 Polyclonal unconjugated

anti-Sine Oculis-Related Homeobox 3 (SIX3) (C-Term) antibody
SIX3 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Mouse, Rat, Human

说明

We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
抗原

SIX3 (Sine Oculis-Related Homeobox 3 (SIX3))

别名

SIX3

背景

Synonyms: Homeobox protein SIX3,Sine oculis homeobox homolog 3,SIX3,
Tissue Specificity: Highly expressed in placenta, lung, kidney, testis and ovary. Weakly expressed in spleen and thymus. Not expressed in peripheral blood lymphocytes. Detected in hippocampus.
Background: Homeobox protein SIX3 is a protein that in humans is encoded by the SIX3 gene. This gene encodes a member of the sine oculishomeobox transcription factor family. The encoded protein plays a role in eye development. Mutations in SIX3 are the cause of a severe brain malformation, called holoprosencephaly type 2 (HPE2). In HPE2, the brain fails to separate into two hemispheres during early embryonic development, leading to eye and brain malformations, which result in serious facial abnormalities. A mutant zebrafish knockout model has been developed, in which the anterior part of the head was missing due to the atypical increase of Wnt1 activity. When injected with SIX3, these zebrafish embryos were able to successfully develop a normal forebrain. When SIX3 was turned off in mice, resulting in a lack of retina formation due to excessive expression of Wnt8b in the region where the forebrain normally develops. Both of these studies demonstrate the importance of SIX3 activity in brain and eye development.

分子量

35 kDa

基因ID

6496

UniProt

O95343

途径

Protein targeting to Nucleus

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