NOV 抗体 (C-Term)
Quick Overview for NOV 抗体 (C-Term) (ABIN5518938)
抗原
See all NOV 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 334-357, C-Term
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原理
- Anti-NOV/CCN3 Antibody Picoband®
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序列
- HTNCPKNNEA FLQELELKTT RGKM
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-NOV/CCN3 Antibody Picoband® (ABIN5518938). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human NOV/CCN3, different from the related mouse sequence by seven amino acids, and from the related rat sequence by four amino acids.
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亚型
- IgG
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anti-Nephroblastoma Overexpressed (NOV) (Center) antibody
NOV 适用: 人, 小鼠 WB, IHC (p), ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Nephroblastoma Overexpressed (NOV) (AA 1-357) antibodyNOV 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Nephroblastoma Overexpressed (NOV) (AA 32-131) antibodyNOV 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 2G8 unconjugated
anti-Nephroblastoma Overexpressed (NOV) (AA 1-357) antibodyNOV 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3C2 unconjugated
anti-Nephroblastoma Overexpressed (NOV) (AA 334-357) antibodyNOV 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nephroblastoma Overexpressed (NOV) (AA 221-320) antibodyNOV 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Nephroblastoma Overexpressed (NOV) antibodyNOV 适用: 人 WB, IHC, ELISA, IP, IHC (p) 宿主: 小鼠 Monoclonal 2G8 unconjugated
anti-Nephroblastoma Overexpressed (NOV) (AA 156-351) antibodyNOV 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nephroblastoma Overexpressed (NOV) (AA 32-357) antibodyNOV 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Nephroblastoma Overexpressed (NOV) (C-Term) antibodyNOV 适用: 人, 小鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Rat
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Jun JI, Lau LF (Dec 2011). "Taking aim at the extracellular matrix: CCN proteins as emerging therapeutic targets". Nature Reviews. Drug Discovery. 10 (12): 945-63. 2. Martinerie C, Viegas-Pequignot E, Guenard I, Dutrillaux B, Nguyen VC, Bernheim A, Perbal B (Dec 1992). "Physical mapping of human loci homologous to the chicken nov proto-oncogene". Oncogene. 7 (12): 2529-34. -
说明
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We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (SV0002-1) for IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- NOV (Nephroblastoma Overexpressed (NOV))
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别名
- NOV
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背景
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Synonyms: Protein NOV homolog,NovH,CCN family member 3,Insulin-like growth factor-binding protein 9,IBP-9,IGF-binding protein 9,IGFBP-9,Nephroblastoma-overexpressed gene protein homolog,NOV,CCN3, IGFBP9, NOVH,
Tissue Specificity: Expressed in bone marrow, thymic cells and nephroblastoma. Increased expression in Wilms tumor of the stromal type. .
Background: NOV (nephroblastoma overexpressed), also known as CCN3, is a matricellular protein that in humans is encoded by the NOV gene. The protein encoded by this gene is a small secreted cysteine-rich protein and a member of the CCN family of regulatory proteins. CNN family proteins associate with the extracellular matrix and play an important role in cardiovascular and skeletal development, fibrosis and cancer development.
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分子量
- 47 kDa
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基因ID
- 4856
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UniProt
- P48745
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途径
- Smooth Muscle Cell Migration, Growth Factor Binding
抗原
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