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MAK 抗体 (C-Term)

This anti-MAK antibody is a 兔 多克隆 antibody detecting MAK in WB. Suitable for 人.
产品编号 ABIN5518933
发货至: 中国

Quick Overview for MAK 抗体 (C-Term) (ABIN5518933)

抗原

See all MAK 抗体
MAK (Male Germ Cell-Associated Kinase (MAK))

适用

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宿主

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克隆类型

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多克隆

标记

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This MAK antibody is un-conjugated

应用范围

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Western Blotting (WB)
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    AA 588-623, C-Term

    原理

    Anti-MAK Antibody Picoband®

    序列

    RTYNPTAKNL NIVNRAQPIP SVHGRTDWVA KYGGHR

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-MAK Antibody Picoband® (ABIN5518933). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human MAK, different from the related mouse and rat sequences by two amino acids.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human
    1. Ma AH, Xia L, Desai SJ, Boucher DL, Guan Y, Shih HM, Shi XB, deVere White RW, Chen HW, Tepper CG, Kung HJ (Sep 2006). "Male germ cell-associated kinase, a male-specific kinase regulated by androgen, is a coactivator of androgen receptor in prostate cancer cells". Cancer Res. 66 (17): 8439-47. 2. Matsushime H, Jinno A, Takagi N, Shibuya M (1990)."A novel mammalian protein kinase gene (mak) is highly expressed in testicular germ cells at and after meiosis". Mol. Cell. Biol. 10 (5): 2261-8.

    说明

    We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    MAK (Male Germ Cell-Associated Kinase (MAK))

    别名

    MAK

    背景

    Synonyms: Serine/threonine-protein kinase MAK,2.7.11.22,Male germ cell-associated kinase,MAK,

    Tissue Specificity: Expressed in prostate cancer cell lines at generally higher levels than in normal prostate epithelial cell lines. Isoform 1 is expressed in kidney, testis, lung, trachea, and retina. Isoform 2 is retina-specific where it is expressed in rod and cone photoreceptors. .

    Background: Serine/threonine-protein kinase MAK is an enzyme that in humans is encoded by the MAK gene. The product of this gene is a serine/threonine protein kinase related to kinases involved in cell cycle regulation. Studies of the mouse and rat homologs have localized the kinase to the chromosomes during meiosis in spermatogenesis, specifically to the synaptonemal complex that exists while homologous chromosomes are paired. Mutations in this gene have been associated with ciliary defects resulting in retinitis pigmentosa 62.

    分子量

    70 kDa

    基因ID

    4117

    UniProt

    P20794
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