HOXB1 抗体 (C-Term)
Quick Overview for HOXB1 抗体 (C-Term) (ABIN5518919)
抗原
See all HOXB1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 176-220, C-Term
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原理
- Anti-HOXB1 Antibody Picoband®
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序列
- TARTFDWMKV KRNPPKTAKV SEPGLGSPSG LRTNFTTRQL TELEK
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-HOXB1 Antibody Picoband® (ABIN5518919). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human HOXB1, different from the related mouse sequence by four amino acids.
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亚型
- IgG
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. Iimura, T., Pourquie, O. Collinear activation of Hoxb genes during gastrulation is linked to mesoderm cell ingression. Nature 442: 568-571, 2006. 2. Goddard, J. M., Rossel, M., Manley, N. R., Capecchi, M. R. Mice with targeted disruption of Hoxb-1 fail to form the motor nucleus of the VIIth nerve. Development 122: 3217-3228, 1996. 3. Webb, B. D., Shaaban, S., Gaspar, H., Cunha, L. F., Schubert, C. R., Hao, K., Robson, C. D., Chan, W.-M., Andrews, C., MacKinnon, S., Oystreck, D. T., Hunter, D. G., Iacovelli, A. J., Ye, X., Camminady, A., Engle, E. C., Jabs, E. W. HOXB1 founder mutation in humans recapitulates the phenotype of Hoxb1-/- mice. Am. J. Hum. Genet. 91: 171-179, 2012. -
说明
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We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- HOXB1 (Homeobox B1 (HOXB1))
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别名
- HOXB1
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背景
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Synonyms: Homeobox protein Hox-B1,Homeobox protein Hox-2I,HOXB1,HOX2I,
Background: Homeobox protein Hox-B1 is a protein that in humans is encoded by the HOXB1 gene. This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXB genes located in a cluster on chromosome 17.
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分子量
- 32 kDa
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基因ID
- 3211
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UniProt
- P14653
抗原
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