GAS6 抗体 (AA 488-660)
Quick Overview for GAS6 抗体 (AA 488-660) (ABIN5518836)
抗原
See all GAS6 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 488-660
-
原理
- Anti-GAS 6/GAS6 Antibody Picoband®
-
交叉反应 （详细）
- No cross-reactivity with other proteins.
-
产品特性
- Anti-GAS 6/GAS6 Antibody Picoband® (ABIN5518836). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human GAS 6 recombinant protein (Position: M488-S660). Human GAS 6 shares 79.7% and 81.4% amino acid (aa) sequence identity with mouse and rat GAS 6, respectively.
-
亚型
- IgG
-
-
anti-Growth Arrest-Specific 6 (GAS6) (AA 483-646) antibody
GAS6 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Growth Arrest-Specific 6 (GAS6) (AA 551-650) antibodyGAS6 适用: 人, 小鼠, Pig WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Growth Arrest-Specific 6 (GAS6) (AA 136-311) antibodyGAS6 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Growth Arrest-Specific 6 (GAS6) (AA 503-664) antibodyGAS6 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Growth Arrest-Specific 6 (GAS6) (AA 59-221) antibodyGAS6 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Growth Arrest-Specific 6 (GAS6) (AA 1-678) antibodyGAS6 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Growth Arrest-Specific 6 (GAS6) (AA 100-300) antibodyGAS6 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Growth Arrest-Specific 6 (GAS6) (AA 100-312) antibodyGAS6 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Growth Arrest-Specific 6 (GAS6) (AA 70-217) antibodyGAS6 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Growth Arrest-Specific 6 (GAS6) (AA 579-678) antibodyGAS6 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.1-0.5 μg/mL, Mouse, Rat, Human
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse, Rat, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Mark MR, Chen J, Hammonds RG, Sadick M, Godowsk PJ (Apr 1996). "Characterization of Gas6, a member of the superfamily of G domain-containing proteins, as a ligand for Rse and Axl". J. Biol. Chem. 271 (16): 9785-9. 2. Nagata K, Ohashi K, Nakano T, Arita H, Zong C, Hanafusa H, Mizuno K (Nov 1996). "Identification of the product of growth arrest-specific gene 6 as a common ligand for Axl, Sky, and Mer receptor tyrosine kinases". J. Biol. Chem. 271 (47): 30022-7. -
说明
-
Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
-
-
- GAS6 (Growth Arrest-Specific 6 (GAS6))
-
别名
- GAS6
-
背景
-
Synonyms: Growth arrest-specific protein 6,GAS-6,AXL receptor tyrosine kinase ligand,GAS6,AXLLG,
Tissue Specificity: Plasma. Isoform 1 and isoform 2 are widely expressed. Isoform 1 is the predominant form in spleen. .
Background: Growth arrest-specific 6, also known as GAS6, is a human gene coding for the Gas6 protein. It is similar to the Protein S with the same domain organization and 43 % amino acid identity. It was originally found as a gene upregulated by growth arrested fibroblasts. This gene is frequently overexpressed in many cancers and has been implicated as an adverse prognostic marker. Elevated protein levels are additionally associated with a variety of disease states, including venous thromboembolic disease, systemic lupus erythematosus, chronic renal failure, and preeclampsia.
-
分子量
- 75 kDa
-
基因ID
- 2621
-
UniProt
- Q14393
-
途径
- RTK signaling, Carbohydrate Homeostasis, Production of Molecular Mediator of Immune Response
抗原
-
