DVL2 抗体 (N-Term)
Quick Overview for DVL2 抗体 (N-Term) (ABIN5518826)
抗原
See all DVL2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 35-64, N-Term
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原理
- Anti-Dishevelled 2/DVL2 Antibody Picoband®
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序列
- AERITLGDFK SVLQRPAGAK YFFKSMDQDF
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-Dishevelled 2/DVL2 Antibody Picoband® (ABIN5518826). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human Dishevelled 2, identical to the related mouse sequence.
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亚型
- IgG
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应用备注
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Western blot, 0.1-0.5 μg/mL, Mouse, Rat, Human
1. Greco TL, Sussman DJ, Camper SA (January 1997). "Dishevelled-2 maps to human chromosome 17 and distal to Wnt3a and vestigial tail (vt) on mouse chromosome 11". Mamm Genome. 7 (6): 475-6. 2. Hocevar, B A, Mou F, Rennolds J L, Morris S M, Cooper J A, Howe P H (June 2003). "Regulation of the Wnt signaling pathway by disabled-2 (Dab2)". EMBO J. England. 22 (12): 3084-94. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- DVL2 (Dishevelled, Dsh Homolog 2 (Drosophila) (DVL2))
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别名
- DVL2
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背景
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Synonyms: Segment polarity protein dishevelled homolog DVL-2,Dishevelled-2,DSH homolog 2,DVL2,
Tissue Specificity: Specifically expressed in endothelial cells. Detected in monocytes, placenta, lung, liver, kidney, skeletal muscle, pancreas, spleen, prostate, small intestine and colon.
Background: Segment polarity protein dishevelled homolog DVL-2 is a protein that in humans is encoded by the DVL2 gene. This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40 % amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans.
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分子量
- 79 kDa
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基因ID
- 1856
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UniProt
- O14641
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途径
- Tube Formation
抗原
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