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DVL2 抗体 (N-Term)

This anti-DVL2 antibody is a 兔 多克隆 antibody detecting DVL2 in WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN5518826
发货至: 中国

Quick Overview for DVL2 抗体 (N-Term) (ABIN5518826)

抗原

See all DVL2 抗体
DVL2 (Dishevelled, Dsh Homolog 2 (Drosophila) (DVL2))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This DVL2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
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    AA 35-64, N-Term

    原理

    Anti-Dishevelled 2/DVL2 Antibody Picoband®

    序列

    AERITLGDFK SVLQRPAGAK YFFKSMDQDF

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-Dishevelled 2/DVL2 Antibody Picoband® (ABIN5518826). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human Dishevelled 2, identical to the related mouse sequence.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Mouse, Rat, Human
    1. Greco TL, Sussman DJ, Camper SA (January 1997). "Dishevelled-2 maps to human chromosome 17 and distal to Wnt3a and vestigial tail (vt) on mouse chromosome 11". Mamm Genome. 7 (6): 475-6. 2. Hocevar, B A, Mou F, Rennolds J L, Morris S M, Cooper J A, Howe P H (June 2003). "Regulation of the Wnt signaling pathway by disabled-2 (Dab2)". EMBO J. England. 22 (12): 3084-94.

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    DVL2 (Dishevelled, Dsh Homolog 2 (Drosophila) (DVL2))

    别名

    DVL2

    背景

    Synonyms: Segment polarity protein dishevelled homolog DVL-2,Dishevelled-2,DSH homolog 2,DVL2,

    Tissue Specificity: Specifically expressed in endothelial cells. Detected in monocytes, placenta, lung, liver, kidney, skeletal muscle, pancreas, spleen, prostate, small intestine and colon.

    Background: Segment polarity protein dishevelled homolog DVL-2 is a protein that in humans is encoded by the DVL2 gene. This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40 % amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans.

    分子量

    79 kDa

    基因ID

    1856

    UniProt

    O14641

    途径

    Tube Formation
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