PDE5A 抗体 (N-Term)
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Quick Overview for PDE5A 抗体 (N-Term) (ABIN5518785)
抗原
See all PDE5A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 20-63, N-Term
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原理
- Anti-PDE5A Antibody
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序列
- QKQQQRDQDS VEAWLDDHWD FTFSYFVRKA TREMVNAWFA ERVH
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交叉反应 (详细)
- No cross-reactivity with other proteins
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产品特性
- Anti-PDE5A Antibody (ABIN5518785). Tested in IHC, WB applications. This antibody reacts with Human, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human PDE5A, different from the related mouse sequence by eight amino acids.
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亚型
- IgG
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Western blot, 0.1-0.5 μg/mL, Human, Rat
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- PDE5A (phosphodiesterase 5A, cGMP-Specific (PDE5A))
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别名
- PDE5A
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背景
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Synonyms: cGMP-specific 3',5'-cyclic phosphodiesterase,3.1.4.35 ,cGMP-binding cGMP-specific phosphodiesterase,CGB-PDE,PDE5A,PDE5,
Tissue Specificity: Expressed in aortic smooth muscle cells, heart, placenta, skeletal muscle and pancreas and, to a much lesser extent, in brain, liver and lung.
Background: cGMP-specific phosphodiesterase type 5 is an enzyme from the phosphodiesterase class. It is found in various tissues, most prominently the corpus cavernosum and the retina. It has also been recently discovered to play a vital role in the cardiovascular system. Furthermore, PDE5A also plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This PDE5A gene is mapped to 4q26.
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分子量
- 100 kDa
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基因ID
- 8654
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UniProt
- O76074
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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