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NOS2 抗体 (C-Term)

Name: NOS2 抗体 (C-Term)
SKU: ABIN5518782
Availability: OutOfStock

NOS2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

Western blot analysis of iNOS expression in HELA whole cell lysates ( Lane 1).

1 image

(17 references)

产品编号 ABIN5518782

发货至: 中国

Datasheet as PDF

抗原 See all NOS2 抗体

NOS2 (Nitric Oxide Synthase 2, Inducible (NOS2))
抗原表位
16

16

12

10

8

6

6

4

4

3

3

3

3

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 1088-1126, C-Term
适用
110

69

69

17

2

1
人
宿主
127

10
兔
Compatible Secondaries
克隆类型
119

18
多克隆
标记
69

16

8

6

4

3

3

3

3

3

3

2

2

2

2

2

2

2

2
This NOS2 antibody is un-conjugated
应用范围
110

45

34

32

27

26

23

18

17

14

8

4

2
Western Blotting (WB)

原理

Rabbit IgG polyclonal antibody for Nitric oxide synthase, inducible(NOS2) detection. Tested with WB in Human.

序列

ARDVAHTLKQ LVAAKLKLNE EQVEDYFFQL KSQKRYHED

交叉反应（详细）

No cross reactivity with other proteins.

产品特性

Rabbit IgG polyclonal antibody for Nitric oxide synthase, inducible(NOS2) detection. Tested with WB in Human.
Gene Name: nitric oxide synthase 2, inducible
Protein Name: Nitric oxide synthase, inducible

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence at the C-terminus of human iNOS (1088-1126aa ARDVAHTLKQLVAAKLKLNEEQVEDYFFQLKSQKRYHED), different from the related mouse sequence by five amino acids, and from the related rat sequence by four amino acids.

亚型

IgG

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anti-Nitric Oxide Synthase 2, Inducible (NOS2) antibody
NOS2 适用: 人, 小鼠 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 4-00E-05 unconjugated

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NOS2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

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anti-Nitric Oxide Synthase 2, Inducible (NOS2) (C-Term) antibody
NOS2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-Nitric Oxide Synthase 2, Inducible (NOS2) (AA 830-860) antibody
NOS2 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB18210 unconjugated

anti-Nitric Oxide Synthase 2, Inducible (NOS2) antibody
NOS2 适用: 人, 小鼠, 大鼠, 小鸡, 犬 WB, IHC (p), IF (p) 宿主: 兔 Polyclonal unconjugated

anti-Nitric Oxide Synthase 2, Inducible (NOS2) (AA 533-696) antibody
NOS2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Nitric Oxide Synthase 2, Inducible (NOS2) (AA 533-696) antibody
NOS2 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C6 unconjugated

应用备注

WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
Liu, Zhang, Han, Wang, Liu, Zhang, Zhou, Xiang: "[Corrigendum] Inhibition of BTK protects lungs from trauma-hemorrhagic shock-induced injury in rats." in: Molecular medicine reports, Vol. 17, Issue 5, pp. 6926, (2018) (PubMed).

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Zhao, Xiong, Mao, Meng, Lei, Li, Deng, Chen, Tu, Lu, Yang, He: "Atmospheric pressure room temperature plasma jets facilitate oxidative and nitrative stress and lead to endoplasmic reticulum stress dependent apoptosis in HepG2 cells." in: PLoS ONE, Vol. 8, Issue 8, pp. e73665, (2013) (PubMed).

Long, Yu, Shuai, Guo, Duan, Xu, Li: "The hypoglycemic effect of the kelp on diabetes mellitus model induced by alloxan in rats." in: International journal of molecular sciences, Vol. 13, Issue 3, pp. 3354-65, (2012) (PubMed).

Zhang, Wei, Wang, Ding, Wang, Shi: "Cell-specific expression and immunolocalization of nitric oxide synthase isoforms and the related nitric oxide/cyclic GMP signaling pathway in the ovaries of neonatal and immature rats." in: Journal of Zhejiang University. Science. B, Vol. 12, Issue 1, pp. 55-64, (2011) (PubMed).

Wang, Du, Wang, Kuang, Wang: "Z-ligustilide attenuates lipopolysaccharide-induced proinflammatory response via inhibiting NF-kappaB pathway in primary rat microglia." in: Acta pharmacologica Sinica, Vol. 31, Issue 7, pp. 791-7, (2010) (PubMed).

Wu, Yin, Yao, Haefliger: "Inhibition by brimonidine of forskolin-induced nitric oxide synthase expression in human ciliary bodies in vitro." in: Molecular vision, Vol. 13, pp. 493-6, (2007) (PubMed).

Sun, Han, Jia, Jiang, Wang, Zhang, Han, Jiang: "Expressions of inducible nitric oxide synthase and matrix metalloproteinase-9 and their effects on angiogenesis and progression of hepatocellular carcinoma." in: World journal of gastroenterology, Vol. 11, Issue 38, pp. 5931-7, (2006) (PubMed).

Wang, Ji, Wang, Gu: "Anti-cancer effect of iNOS inhibitor and its correlation with angiogenesis in gastric cancer." in: World journal of gastroenterology, Vol. 11, Issue 25, pp. 3830-3, (2005) (PubMed).

Xu, Deng, Zhu, Lin: "Role of inducible nitric oxide synthase expression in aberrant crypt foci-adenoma-carcinoma sequence." in: World journal of gastroenterology, Vol. 9, Issue 6, pp. 1246-50, (2003) (PubMed).

Sassenroth, Trinkmann: "[Implantation of a Binkhorst lens in chronic simple glaucoma]." in: Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, Vol. 82, Issue 2, pp. 186, (1985) (PubMed).

Shapiro: "Portrait of a pioneer laryngologist." in: Eye, ear, nose & throat monthly, Vol. 53, Issue 11, pp. 460-4, (1975) (PubMed).

Achten: "Diseases of the dermis. General considerations." in: Archives belges de dermatologie et de syphiligraphie, Vol. 28, Issue 1, pp. 1-13, (1973) (PubMed).
抗原

NOS2 (Nitric Oxide Synthase 2, Inducible (NOS2))

别名

NOS2 (NOS2 产品)

别名

HEP-NOS antibody, INOS antibody, NOS antibody, NOS2A antibody, NOS-II antibody, Nos-2 antibody, Nos2a antibody, i-NOS antibody, iNOS antibody, iNos antibody, NOS2a antibody, NOS2 antibody, BmNOS2 antibody, Nsl antibody, nos2 antibody, nitric oxide synthase 2 antibody, nitric oxide synthase 2, inducible antibody, inducible nitric oxide synthase antibody, inducible nitric-oxide synthase antibody, nanos C2HC-type zinc finger 2 antibody, NOS2 antibody, Nos2 antibody, nos2 antibody, LOC396821 antibody, NANOS2 antibody

背景

Nitric oxide synthase, inducible is an enzyme that in humans is encoded by the NOS2 gene. Nitric oxide (NO) is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter, it is implicated in neurotoxicity associated with stroke and neurodegenerative diseases, neural regulation of smooth muscle, including peristalsis, and penile erection. Three different NOS isoforms have been identified which fall into two distinct types, constitutive and inducible. The inducible NOS (iNOS) isoform is expressed in a variety of cell types and tissues in response to inflammatory agents and cytokines. The human iNOS (NOS2) gene is approximately 37 kb in length and consists of 26 exons and 25 introns. NOS2-derived NO is a prerequisite for cytokine signaling and function in innate immunity.

Synonyms: Ascites | HEP NOS | Hepatocyte NOS | HEPNOS | HEP-NOS | Inducible NOS | iNOS | NANOS2 | nitric oxide synthase 2, inducible | NOS 2A | NOS2A | P60321

基因ID

4843

UniProt

P35228

途径

Retinoic Acid Receptor Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Inositol Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process