ISL1 抗体 (Middle Region)
Quick Overview for ISL1 抗体 (Middle Region) (ABIN5518765)
抗原
See all ISL1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 118-161, Middle Region
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原理
- Anti-Islet 1/ISL1 Antibody Picoband®
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序列
- DEFALREDGL FCRADHDVVE RASLGAGDPL SPLHPARPLQ MAAE
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Islet 1/ISL1 Antibody Picoband® (ABIN5518765). Tested in IHC, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human Islet 1, identical to the related mouse and rat sequences.
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亚型
- IgG
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anti-ISL LIM Homeobox 1 (ISL1) (AA 63-159) antibody
ISL1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2E7 unconjugated
anti-ISL LIM Homeobox 1 (ISL1) (AA 63-159) antibodyISL1 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 1A3 unconjugated
anti-ISL LIM Homeobox 1 (ISL1) antibodyISL1 适用: 人 ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 1H9 unconjugated
anti-ISL LIM Homeobox 1 (ISL1) antibodyISL1 适用: 人 WB, ELISA, IHC 宿主: 兔 Monoclonal 1A1 unconjugated Recombinant Antibody
anti-ISL LIM Homeobox 1 (ISL1) antibodyMicroarray verified ISL1 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB381223 unconjugated
anti-ISL LIM Homeobox 1 (ISL1) (AA 1-346) antibodyISL1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-ISL LIM Homeobox 1 (ISL1) (AA 63-159) antibodyISL1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4A7 unconjugated
anti-ISL LIM Homeobox 1 (ISL1) antibodyISL1 适用: 人 WB, IF, ICC, IHC (p), IHC (fro), IHC (wm) 宿主: 兔 Polyclonal unconjugated
anti-ISL LIM Homeobox 1 (ISL1) (AA 63-159) antibodyISL1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5F12 unconjugated
anti-ISL LIM Homeobox 1 (ISL1) antibodyISL1 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Western blot, 0.1-0.5 μg/mL, Human, Rat
1. "Entrez Gene: ISL1 ISL1 transcription factor, LIM/homeodomain, (islet-1)". 2. Gay F, Anglade I, Gong Z, Salbert G (October 2000). "The LIM/homeodomain protein islet-1 modulates estrogen receptor functions". Mol. Endocrinol. 14 (10): 1627-48. 3. Tanizawa Y, Riggs AC, Dagogo-Jack S, Vaxillaire M, Froguel P, Liu L, Donis-Keller H, Permutt MA (July 1994). "Isolation of the human LIM/homeodomain gene islet-1 and identification of a simple sequence repeat polymorphism [corrected]". Diabetes. 43 (7): 935-41. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- ISL1 (ISL LIM Homeobox 1 (ISL1))
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别名
- ISL1
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背景
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Synonyms: Insulin gene enhancer protein ISL-1,Islet-1,ISL1,
Tissue Specificity: Expressed in subsets of neurons of the adrenal medulla and dorsal root ganglion, inner nuclear and ganglion cell layers in the retina, the pineal and some regions of the brain.
Background: Insulin gene enhancer protein ISL-1 is a protein that in humans is encoded by the isl1 gene. This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young.
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分子量
- 39 kDa
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基因ID
- 3670
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UniProt
- P61371
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途径
- Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding
抗原
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