IL-13 抗体 (AA 36-146)
(5 references)Quick Overview for IL-13 抗体 (AA 36-146) (ABIN5518763)
抗原
See all IL-13 (IL13) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 36-146
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原理
- Anti-IL13 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-IL13 Antibody Picoband® (ABIN5518763). Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived human IL13 recombinant protein (Position: P36-N146). Human IL13 shares 55.3% and 61.9% amino acid (aa) sequence identity with mouse and rat IL13, respectively.
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亚型
- IgG
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anti-Interleukin 13 (IL13) (AA 45-56) antibody
IL13 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 13 (IL13) (AA 25-146) antibodyIL13 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 13 (IL13) (AA 25-146) antibodyIL13 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 13 (IL13) antibodyIL13 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2B5 unconjugated
anti-Interleukin 13 (IL13) (AA 118-146) antibodyIL13 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 13 (IL13) (AA 25-131) antibodyIL13 适用: Pig WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 13 (IL13) (AA 30-125) antibodyIL13 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 13 (IL13) antibodyIL13 适用: 大鼠 ELISA, IHC, FACS, IHC (p) 宿主: 小鼠 Monoclonal A130D 12G5 1E4 unconjugated
anti-Interleukin 13 (IL13) antibodyIL13 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 7A7 unconjugated
anti-Interleukin 13 (IL13) antibodyIL13 适用: 人 WB, ELISA, IHC, Neut, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Western blot, 0.1-0.5 μg/mL, Human
1. Blackburn, M. R., Lee, C. G., Young, H. W. J., Zhu, Z., Chunn, J. L., Kang, M. J., Banerjee, S. K., Elias, J. A.Adenosine mediates IL-13-induced inflammation and remodeling in the lung and interacts in an IL-13-adenosine amplification pathway. 2. Paul, W. E.Personal Communication.Bethesda, Md. 3/6/1993. 3. Punnonen, J., Aversa, G., Cocks, B. G., McKenzie, A. N. J., Menon, S., Zurawski, G., de Waal Malefyt, R., de Vries, J. E.Interleukin 13 induces interleukin 4-independent IgG4 and IgE synthesis and CD23 expression by human B cells.Proc. Nat. Acad. Sci. 90: 3730-3734, 1993. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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: "Number 2 Feibi Recipe Reduces PM2.5-Induced Lung Injury in Rats." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2018, pp. 3674145, (2018) (PubMed).
: "Acute exposure of ozone induced pulmonary injury and the protective role of vitamin E through the Nrf2 pathway in Balb/c mice." in: Toxicology research, Vol. 5, Issue 1, pp. 268-277, (2018) (PubMed).
: "CD68 and interleukin 13, prospective immune markers for esophageal squamous cell carcinoma prognosis prediction." in: Oncotarget, Vol. 7, Issue 13, pp. 15525-38, (2017) (PubMed).
: "Th17 down-regulation is involved in reduced progression of schistosomiasis fibrosis in ICOSL KO mice." in: PLoS neglected tropical diseases, Vol. 9, Issue 1, pp. e0003434, (2016) (PubMed).
: "An IL-13 promoter polymorphism associated with liver fibrosis in patients with Schistosoma japonicum." in: PLoS ONE, Vol. 10, Issue 8, pp. e0135360, (2016) (PubMed).
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: "Number 2 Feibi Recipe Reduces PM2.5-Induced Lung Injury in Rats." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2018, pp. 3674145, (2018) (PubMed).
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- IL-13 (IL13) (Interleukin 13 (IL13))
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别名
- IL13
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背景
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Synonyms: Interleukin-13,IL-13,IL13,NC30,
Tissue Specificity: Widely expressed, including in adult and fetal brain, placenta, skin fibroblasts, adipose tissue and gonads.
Background: Interleukin 13 is a protein that in humans is encoded by the IL-13 gene. It is a kind of cytokine secreted by many cell types, but especially T helper type 2 (Th2) cells, which is an important mediator of allergic inflammation and disease. The IL-13 gene is mapped to 5q23-q31. IL-13 induces its effects through a multi-subunit receptor that includes the alpha chain of the IL-4 receptor (IL-4Rα) and at least one of two known IL-13-specific binding chains. Furthermore, this gene acts more prominently as a molecular bridge linking allergic inflammatory cells to the non-immune cells in contact with them, thereby altering physiological function.
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分子量
- 20 kDa
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基因ID
- 3596
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UniProt
- P35225
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途径
- JAK/STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport
抗原
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