CKAP4 抗体 (N-Term)
Quick Overview for CKAP4 抗体 (N-Term) (ABIN5518750)
抗原
See all CKAP4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 95-118, N-Term
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原理
- Anti-CKAP4 Antibody Picoband®
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序列
- LVAAAAFSGW YVHHVLEEVQ QVRR
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-CKAP4 Antibody Picoband® (ABIN5518750). Tested in WB applications. This antibody reacts with Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of mouse CKAP4, different from the related human sequence by one amino acid.
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亚型
- IgG
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应用备注
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Western blot, 0.1-0.5 μg/mL, Mouse
1. "Entrez Gene: CKAP4 cytoskeleton-associated protein 4". 2. Schweizer A, Rohrer J, Jeno P, DeMaio A, Buchman TG, Hauri HP (Jul 1993). "A reversibly palmitoylated resident protein (p63) of an ER-Golgi intermediate compartment is related to a circulatory shock resuscitation protein". J Cell Sci. 104 (3): 685-94. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- CKAP4 (Cytoskeleton-Associated Protein 4 (CKAP4))
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别名
- Ckap4
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背景
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Synonyms: Cytoskeleton-associated protein 4,63- kDa cytoskeleton-linking membrane protein,Climp-63,p63,Ckap4,
Tissue Specificity: High in intestine and in peripheral blood mononuclear cells, low in lung, kidney, thymus, uterus, vasculature and brain. Not found in liver, heart, retina oe skeletal muscle.
Background: Cytoskeleton-associated protein 4, also known as CLIMP63 and p63, is a protein that in humans is encoded by the CKAP4 gene. It is mapped to 12q23.3. CKAP4 is found on the plasma membrane of select cells such as vascular smooth muscle and Type II Greater alveolar lung cells. It has a bimodal distribution. First, CKAP4 is found on the plasma membrane and serves as a receptor for SP-A/surfactant protein-A (in lung) and tPA (in vessels). Second, it is embedded in the membrane of a compartment that links the ER with the Golgi apparatus. This localization is dependent on its ability to form homooligomers, and its presence serves to anchor microtubules and the formation of tubular ER.
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分子量
- 66 kDa
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基因ID
- 216197
抗原
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