(4 references)-
- 抗原 See all CDK6 抗体
- CDK6 (Cyclin-Dependent Kinase 6 (CDK6))
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抗原表位
- AA 291-310, C-Term
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CDK6 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 原理
- Rabbit IgG polyclonal antibody for Cyclin-dependent kinase 6(CDK6) detection. Tested with WB in Human,Rat,Mouse.
- 序列
- AYGALNHPYF QDLERYKDNL
- 交叉反应 （详细）
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Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities. - 产品特性
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Rabbit IgG polyclonal antibody for Cyclin-dependent kinase 6(CDK6) detection. Tested with WB in Human,Rat,Mouse.
Gene Name: cyclin-dependent kinase 6
Protein Name: Cyclin-dependent kinase 6 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of mouse Cdk6(291-310aa AYGALNHPYFQDLERYKDNL), identical to the related rat sequence, and different from the related human sequence by four amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product CDK6 Primary Antibody
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anti-Cyclin-Dependent Kinase 6 (CDK6) (AA 3-99) antibody
CDK6 适用: 人 WB, IF, ELISA, IHC (p), PLA 宿主: 小鼠 Monoclonal 8H4 unconjugated
anti-Cyclin-Dependent Kinase 6 (CDK6) antibodyCDK6 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 6 (CDK6) (AA 1-326) antibodyCDK6 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 6 (CDK6) antibodyKO Validated CDK6 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 6 (CDK6) (AA 280-325) antibodyCDK6 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 6 (CDK6) (pTyr13) antibodyCDK6 适用: 人 WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 6 (CDK6) antibodyCDK6 适用: 人, 大鼠 WB, IF, IHC (p), EIA 宿主: 小鼠 Monoclonal 8H4 unconjugated
anti-Cyclin-Dependent Kinase 6 (CDK6) (AA 21-110) antibodyCDK6 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro), FACS 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 6 (CDK6) antibodyCDK6 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Monoclonal 4F7 unconjugated
anti-Cyclin-Dependent Kinase 6 (CDK6) (pTyr24) antibodyCDK6 适用: 人 WB, IHC, IF, ELISA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Sodium azide, Thimerosal (Merthiolate)
- 注意事项
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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: "TALENs-directed knockout of the full-length transcription factor Nrf1α that represses malignant behaviour of human hepatocellular carcinoma (HepG2) cells." in: Scientific reports, Vol. 6, pp. 23775, (2017) (PubMed).
: "Long noncoding RNA NEAT1 promotes laryngeal squamous cell cancer through regulating miR-107/CDK6 pathway." in: Journal of experimental & clinical cancer research : CR, Vol. 35, pp. 22, (2016) (PubMed).
: "Isoflavone lupiwighteone induces cytotoxic, apoptotic, and antiangiogenic activities in DU-145 prostate cancer cells." in: Anti-cancer drugs, Vol. 26, Issue 6, pp. 599-611, (2015) (PubMed).
: "Platycodin D induces tumor growth arrest by activating FOXO3a expression in prostate cancer in vitro and in vivo." in: Current cancer drug targets, Vol. 14, Issue 9, pp. 860-71, (2015) (PubMed).
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: "TALENs-directed knockout of the full-length transcription factor Nrf1α that represses malignant behaviour of human hepatocellular carcinoma (HepG2) cells." in: Scientific reports, Vol. 6, pp. 23775, (2017) (PubMed).
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- 抗原
- CDK6 (Cyclin-Dependent Kinase 6 (CDK6))
- 别名
- CDK6 (CDK6 产品)
- 别名
- CDK6 antibody, PLSTIRE antibody, 5830411I20 antibody, AI504062 antibody, Crk2 antibody, cyclin dependent kinase 6 antibody, cyclin-dependent kinase 6 antibody, CDK6 antibody, Cdk6 antibody
- 背景
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Cell division protein kinase 6, also called Plstire, is an enzyme that in humans is encoded by the CDK6 gene. The protein encoded by this gene is a member of the cyclin-dependent protein kinase(CDK) family. Radiation hybrid analysis and inclusion within a mapped clone place the CDK6 gene at 7q21. Serine/threonine-protein kinase involved in the control of the cell cycle and differentiation and promotes G1/S transition. This gene also involved in initiation and maintenance of cell cycle exit during cell differentiation. It prevents cell proliferation and regulates negatively cell differentiation, but is required for the proliferation of specific cell types. CDK6 also plays a role in promoting the proliferation of beta-cells in pancreatic islets of Langerhans.
Synonyms: CDK 6 antibody|CDK6 antibody|CDK6_HUMAN antibody|Cell division protein kinase 6 antibody|Crk 2 antibody|Crk2 antibody|Cyclin dependent kinase 6 antibody|Cyclin-dependent kinase 6 antibody|MGC59692 antibody|p40 antibody|PLSTIRE antibody|Serine/threonine protein kinase PLSTIRE antibody|Serine/threonine-protein kinase PLSTIRE antibody|STQTL11 antibody - UniProt
- Q64261
- 途径
- Cell Division Cycle, Mitotic G1-G1/S Phases
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