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CD80 抗体 (C-Term)

This anti-CD80 antibody is a 兔多克隆 antibody detecting CD80 in WB. Suitable for 大鼠. This Primary Antibody has been cited in 1 publication.

Anti- CD80 antibody, Western blottingAll lanes: Anti CD80 at 0. (CD80 抗体 (C-Term))

1 image

(1 reference)

产品编号 ABIN5518665

发货至: 中国

Quick Overview for CD80 抗体 (C-Term) (ABIN5518665)

抗原

See all CD80 抗体

CD80

适用

182
96
44
6
6
6
1
1
1

大鼠

宿主

兔

克隆类型

多克隆

标记

This CD80 antibody is un-conjugated

应用范围

129
93
72
35
35
23
14
13
13
12
11
10
7
5
4
2
2
2
1
1
1
1
1

Western Blotting (WB)

Discover our top product CD80 Primary Antibody

抗原表位
34

16

15

12

8

6

6

4

4

4

3

3

3

2

2

1

1

1

1

1

1

1

1

1

1
AA 227-245, C-Term

原理

Anti-CD80 Antibody Picoband®

序列

DAHVSQNFTW EKPPEDPPD

交叉反应（详细）

No cross-reactivity with other proteins

产品特性

Anti-CD80 Antibody (ABIN5518665). Tested in WB applications. This antibody reacts with Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence at the C-terminus of rat CD80, different from the related mouse sequence by two amino acids.

亚型

IgG
anti-CD80 (CD80) (AA 35-288) antibody
CD80 适用: 人 FACS, ELISA, IHC 宿主: 小鼠 Monoclonal 1G3D7 unconjugated

anti-CD80 (CD80) (AA 251-321) antibody
CD80 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), ICC, IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated

anti-CD80 (CD80) antibody
CD80 适用: 小鼠, 犬 FACS, IP, IHC (fro) 宿主: 仓鼠 Monoclonal 16-10A1 unconjugated

anti-CD80 (CD80) (Extracellular Domain) antibody
CD80 适用: 人 FACS, IP 宿主: 小鼠 Monoclonal MEM-233 unconjugated

anti-CD80 (CD80) (Extracellular Domain) antibody (FITC)
CD80 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-233 FITC

anti-CD80 (CD80) (Extracellular Domain) antibody (PerCP)
CD80 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-233 PerCP

anti-CD80 (CD80) (Extracellular Domain) antibody (PE)
CD80 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-233 PE

anti-CD80 (CD80) (Extracellular Domain) antibody (APC)
CD80 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-233 APC

anti-CD80 (CD80) antibody
CD80 适用: 人 ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 2A2 unconjugated

anti-CD80 (CD80) (AA 111-265) antibody
CD80 适用: 人, 小鼠, 大鼠 FACS, WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Rat
1. Peach, R J, Bajorath J, Naemura J, Leytze G, Greene J, Aruffo A, Linsley P S (Sep. 1995). "Both extracellular immunoglobin-like domains of CD80 contain residues critical for binding T cell surface receptors CTLA-4 and CD28". J. Biol. Chem. (UNITED STATES) 270 (36): 21181-7. 2. Stamper, C C, Zhang Y, Tobin J F, Erbe D V, Ikemizu S, Davis S J, Stahl M L, Seehra J, Somers W S, Mosyak L (Mar. 2001). "Crystal structure of the B7-1/CTLA-4 complex that inhibits human immune responses". Nature (England) 410 (6828): 608-11.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

储存液

Sodium azide, Thimerosal (Merthiolate)

注意事项

This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Du, Dong, Zhao, Fu, Wang, Chen, Ou, Li, Sun, Tang, Song: "Immunostimulatory and anti-neoplasm effects of a novel palindrome CpG oligodeoxynucleotide in mice." in: Acta pharmacologica Sinica, Vol. 33, Issue 8, pp. 1047-54, (2012) (PubMed).
抗原

CD80

别名

CD80

背景

Synonyms: CD80 ,
Background: Cluster of Differentiation 80 (also CD80 and B7-1) is a protein found on activated B cells and monocytes that provides a costimulatory signal necessary for T cell activation and survival. It is the ligand for two different proteins on the T cell surface: CD28 (for autoregulation and intercellular association) and CTLA-4 (for attenuation of regulation and cellular disassociation). CD80 works in tandem with CD86 to prime T cells. The CD80 genes encode B7-1 which are structurally similar members of the immunoglobulin superfamily expressed on a variety of hematopoietic cell types. Reeves et al. (1997) stated that B7-1 and B7-2 provide a costimulatory signal to T cells by interacting with CD28 and CTLA4.

分子量

50 kDa

UniProt

O55202

途径

TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints

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