ZCCHC6 抗体 (N-Term)
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Quick Overview for ZCCHC6 抗体 (N-Term) (ABIN5517595)
抗原
See all ZCCHC6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- SPENKKQRSR PRKPRKTRNE ENEQDGDLEG PVIDESVLST KELLGLQQAE
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纯化方法
- Affinity purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human ZCCHC6
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ZCCHC6 (Zinc Finger, CCHC Domain Containing 6 (ZCCHC6))
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别名
- ZCCHC6
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背景
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Uridylyltransferase that mediates the terminal uridylation of mRNAs with short (less than 25 nucleotides) poly(A) tails, hence facilitating global mRNA decay. Involved in microRNA (miRNA)-induced gene silencing through uridylation of deadenylated miRNA targets. Also acts as a suppressor of miRNA biogenesis by mediating the terminal uridylation of some miRNA precursors, including that of let-7 (pre-let-7). Uridylated pre-let-7 RNA is not processed by Dicer and undergo degradation. Pre-let-7 uridylation is strongly enhanced in the presence of LIN28A. Due to functional redundancy between ZCCHC6 and ZCCHC11, the identification of the specific role of each of these proteins is difficult.
Alias Symbols: TUT7, PAPD6
Protein Size: 544 -
基因ID
- 79670
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NCBI登录号
- NM_001185059, NP_001171988
抗原
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