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ZCCHC6 抗体

ZCCHC6 适用: 人, 小鼠, 大鼠 WB, IP, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7121053
发货至: 中国
  • 抗原 See all ZCCHC6 抗体
    ZCCHC6 (Zinc Finger, CCHC Domain Containing 6 (ZCCHC6))
    适用
    人, 小鼠, 大鼠
    宿主
    • 3
    • 2
    克隆类型
    • 5
    多克隆
    标记
    • 5
    This ZCCHC6 antibody is un-conjugated
    应用范围
    Western Blotting (WB), Immunoprecipitation (IP), ELISA
    纯化方法
    Immunogen affinity purified
    纯度
    ≥95 % as determined by SDS-PAGE
    免疫原
    zinc finger, CCHC domain containing 6
    亚型
    IgG
    Top Product
    Discover our top product ZCCHC6 Primary Antibody
  • 应用备注
    WB: 1:500-1:5000, IP: 1:500-1:5000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    有效期
    12 months
  • 抗原
    ZCCHC6 (Zinc Finger, CCHC Domain Containing 6 (ZCCHC6))
    别名
    ZCCHC6 (ZCCHC6 产品)
    别名
    PAPD6 antibody, 6030448M23Rik antibody, AA420405 antibody, zinc finger CCHC-type containing 6 antibody, zinc finger, CCHC domain containing 6 antibody, ZCCHC6 antibody, Zcchc6 antibody
    背景
    Synonyms:DKFZp666B142, DKFZp686C11112, DKFZp686F119, DKFZp686I1269, HS2, KIAA1711, PAPD6, Terminal uridylyltransferase 7, TUT7, TUTase 7, ZCCHC6 Background:Uridylyltransferase that mediates the terminal uridylation of mRNAs with short(less than 25 nucleotides) poly(A) tails, hence facilitating global mRNA decay(PubMed:19703396, PubMed:25480299). Involved in microRNA(miRNA)-induced gene silencing through uridylation of deadenylated miRNA targets(PubMed:25480299). Also acts as a suppressor of miRNA biogenesis by mediating the terminal uridylation of some miRNA precursors, including that of let-7(pre-let-7). Uridylated pre-let-7 RNA is not processed by Dicer and undergo degradation. Pre-let-7 uridylation is strongly enhanced in the presence of LIN28A(PubMed:22898984). Due to functional redundancy between ZCCHC6 and ZCCHC11, the identification of the specific role of each of these proteins is difficult.
    分子量
    171 kDa
    基因ID
    79670
    UniProt
    Q5VYS8
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