RSPO1 抗体 (C-Term)
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北京 101111
Quick Overview for RSPO1 抗体 (C-Term) (ABIN5517492)
抗原
See all RSPO1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- RSPO1 Antibody - C-terminal region
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序列
- RCTVRRVPCP EGQKRRKGGQ GRRENANRNL ARKESKEAGA GSRRRKGQQQ
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预测反应
- Cow: 85%, Dog: 92%, Goat: 85%, Horse: 92%, Human: 100%, Rabbit: 86%
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纯化方法
- Affinity purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human RSPO1
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP64132-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- RSPO1 (R-Spondin 1 (RSPO1))
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别名
- RSPO1
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背景
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Background Information: This gene encodes a secreted activator protein with two cysteine-rich, furin-like domains and one thrombospondin type 1 domain. The encoded protein is a ligand for leucine-rich repeat-containing G-protein coupled receptors (LGR proteins) and positively regulates the Wnt signaling pathway. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects. Alternative splicing results in multiple transcript variants.
Gene Name: R-spondin 1
Alternative Symbols: RSPO, CRISTIN3
Protein Name: R-spondin-1
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分子量
- 25 kDa
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基因ID
- 284654
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NCBI登录号
- NP_001229838
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UniProt
- Q2MKA7
抗原
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