SETD7 抗体 (N-Term)
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- 抗原 See all SETD7 抗体
- SETD7 (SET Domain Containing (Lysine Methyltransferase) 7 (SETD7))
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抗原表位
- N-Term
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适用
- 人, 小鼠, 大鼠, 犬, 马, Pig, 兔, Cow, 斑马鱼, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SETD7 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- MDSDDEMVEE AVEGHLDDDG LPHGFCTVTY SSTDRFEGNF VHGEKNGRGK
- 预测反应
- Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%
- 产品特性
- This is a rabbit polyclonal antibody against SETD7. It was validated on Western Blot.
- 纯化方法
- Affinity purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human SETD7
- Top Product
- Discover our top product SETD7 Primary Antibody
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anti-SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) (AA 257-366) antibody
SETD7 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 5B4 unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) (AA 107-366) antibodySETD7 适用: 人, 大鼠, 猴 WB, ELISA, IHC, FACS, ICC, Neut 宿主: 小鼠 Monoclonal 1B3B8 unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) (AA 107-366) antibodySETD7 适用: 人, 大鼠, 猴 WB, ELISA, IHC, FACS, ICC, Neut 宿主: 小鼠 Monoclonal 3D6G11 unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) (AA 257-366) antibodySETD7 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) antibodySETD7 适用: 人, 小鼠 WB, FACS 宿主: 小鼠 Monoclonal 2E3 unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) antibodySETD7 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal S4E5 unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) (AA 1-366) antibodySETD7 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) (AA 159-189) antibodySETD7 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB2763 unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) (AA 1-218) antibodySETD7 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) (AA 1-366) antibodySETD7 适用: 人 WB, ELISA, FACS, IF, ICC 宿主: 小鼠 Monoclonal s4E5 unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- SETD7 (SET Domain Containing (Lysine Methyltransferase) 7 (SETD7))
- 别名
- SETD7 (SETD7 产品)
- 背景
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SETD7 is a histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. It plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins. Monomethylates 'Lys-189' of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates 'Lys-372' of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation.
Alias Symbols: SETD7, KIAA1717, KMT7, SET7, SET9,
Protein Interaction Partner: KLF4, HIST3H3, SOX2, PRKAR1A, A1BG, TP53, NR2F2, STEAP3, SERTAD1, DPY30, MED1, MYOD1, E2F1, HIST1H3A, SMARCA4, H3F3A, STAT3, RELA, AR, UBC, DNMT1, PPP1R12A, SIRT1, TBP, TAF10, TAF7, TAF6, HIST1H4A, ESR1, HIST2H3C, HCFC1, L3MBTL1,
Protein Size: 366 - 基因ID
- 80854
- NCBI登录号
- NP_085151
- UniProt
- Q8WTS6
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