PDE5A 抗体 (N-Term)
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Quick Overview for PDE5A 抗体 (N-Term) (ABIN5517241)
抗原
See all PDE5A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- MERAGPSFGQ QRQQQQPQQQ KQQQRDQDSV EAWLDDHWDF TFSYFVRKAT
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纯化方法
- Affinity purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human PDE5A
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PDE5A (phosphodiesterase 5A, cGMP-Specific (PDE5A))
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别名
- PDE5A
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背景
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This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms.
Alias Symbols: CN5A, PDE5, CGB-PDE
Protein Size: 875 -
基因ID
- 8654
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NCBI登录号
- NM_001083, NP_001074
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UniProt
- O76074
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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