FBXW5 抗体 (N-Term)
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北京 101111
Quick Overview for FBXW5 抗体 (N-Term) (ABIN5516989)
抗原
See all FBXW5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- NDLTISLLHS ADMRPYNWSY TQFSQFNKDD SLLLASGVFL GPHNSSSGEI
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预测反应
- Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rat: 93%, Zebrafish: 85%
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产品特性
- This is a rabbit polyclonal antibody against FBXW5. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human FBXW5
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- FBXW5 (F-Box and WD Repeat Domain Containing 5 (FBXW5))
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别名
- FBXW5
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背景
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This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene contains WD-40 domains, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene, however, they were found to be nonsense-mediated mRNA decay (NMD) candidates, hence not represented.
Alias Symbols: FBXW5, FBW5, PP3971,
Protein Interaction Partner: KRT40, KRTAP9-4, ADAMTSL4, CUL1, UBC, TRIM27, KRT31, NOTCH2NL, KRTAP10-3, KRTAP10-8, CUL3, SKP1, TNFAIP8L1, TSC2, DLC1, HSP90AA1, NEDD8, MAP3K7, CUL4A, REST, MYB, DDB1, UBE2R2, SASS6, PLK4, CDC20, WDR20, KRTAP4-12, MDFI, TSC1, NLK,
Protein Size: 566 -
基因ID
- 54461
抗原
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