Spindlin 1 抗体 (N-Term)
Quick Overview for Spindlin 1 抗体 (N-Term) (ABIN5516939)
抗原
See all Spindlin 1 (SPIN1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- KTPFGKTPGQ RSRADAGHAG VSANMMKKRT SHKKHRSSVG PSKPVSQPRR
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预测反应
- Cow: 100%, Dog: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against SPIN1. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human SPIN1
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anti-Spindlin 1 (SPIN1) (AA 1-262) antibody
SPIN1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Spindlin 1 (SPIN1) (AA 1-262) antibodySPIN1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Spindlin 1 (SPIN1) (Internal Region) antibodySPIN1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Spindlin 1 (SPIN1) (N-Term) antibodySPIN1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Spindlin 1 (SPIN1) (AA 3-100) antibodySPIN1 适用: 人 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Spindlin 1 (SPIN1) (AA 111-160) antibodySPIN1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Spindlin 1 (SPIN1) (AA 179-228) antibodySPIN1 适用: 人, 小鼠, 大鼠, Pig, Cow, 犬, 兔, 小鸡, 猴, 豚鼠, 斑马鱼, Bat, 非洲爪蟾 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Spindlin 1 (SPIN1) (Middle Region) antibodySPIN1 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 斑马鱼, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Spindlin 1 (SPIN1) (Internal Region) antibodySPIN1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Spindlin 1 (SPIN1)
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别名
- SPIN1
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背景
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SPIN1 is a chromatin reader that specifically recognizes and binds histone H3 both trimethylated at 'Lys-4' and asymmetrically dimethylated at 'Arg-8' (H3K4me3 and H3R8me2a) and acts as an activator of Wnt signaling pathway dowstream of PRMT2. In case of cancer, promotes cell cancer proliferation via activation of the Wnt signaling pathway (PubMed:24589551). Overexpression induces metaphase arrest and chromosomal instability. Localizes to active rDNA loci and promotes the expression of rRNA genes (PubMed:21960006).It may play a role in cell-cycle regulation during the transition from gamete to embryo. Involved in oocyte meiotic resumption, a process that takes place before ovulation to resume meiosis of oocytes blocked in prophase I: may act by regulating maternal transcripts to control meiotic resumption.
Alias Symbols: SPIN1, OCR, SPIN,
Protein Interaction Partner: SUMO2, UBC, PRMT6, BAG3, NPM1, UBL4A, SMURF1, EIF4A3, YWHAE, MAGOH, GRK5, TCF3, ARRB2, ARRB1, ELAVL1, AGO3, PTN,
Protein Size: 262 -
基因ID
- 10927
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NCBI登录号
- NP_006708
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UniProt
- Q9Y657
抗原
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