Spindlin 1 抗体 (AA 3-100)
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- 抗原 See all Spindlin 1 (SPIN1) 抗体
- Spindlin 1 (SPIN1)
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抗原表位
- AA 3-100
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Spindlin 1 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 特异性
- There is 60 % sequence similarity with Spindlin 3, but the sequence is not continuous so the chance of bindin is low.
- 交叉反应
- 人
- 预测反应
- Mouse,Rat
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Spindin 1
- 亚型
- IgG
- Top Product
- Discover our top product SPIN1 Primary Antibody
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anti-Spindlin 1 (SPIN1) (AA 1-262) antibody
SPIN1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Spindlin 1 (SPIN1) (Internal Region) antibodySPIN1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Spindlin 1 (SPIN1) (AA 1-262) antibodySPIN1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Spindlin 1 (SPIN1) (Internal Region) antibodySPIN1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Spindlin 1 (SPIN1) (N-Term) antibodySPIN1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Spindlin 1 (SPIN1) (AA 111-160) antibodySPIN1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Spindlin 1 (SPIN1) (AA 179-228) antibodySPIN1 适用: 人, 小鼠, 大鼠, Pig, 兔, Cow, 犬, 小鸡, 猴, 豚鼠, 斑马鱼, 非洲爪蟾, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Spindlin 1 (SPIN1) (Middle Region) antibodySPIN1 适用: 人, 小鼠, 大鼠, 兔, Cow, 犬, 豚鼠, 斑马鱼, 马 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- Spindlin 1 (SPIN1)
- 别名
- Spindlin 1 (SPIN1 产品)
- 别名
- SPIN antibody, AA553322 antibody, AA673430 antibody, Spin antibody, spin antibody, spindlin antibody, MGC115436 antibody, Spindlin-1 antibody, DKFZp459K085 antibody, spindlin 1 antibody, spindlin 1 L homeolog antibody, SPIN1 antibody, Spin1 antibody, spin1 antibody, spin1.L antibody
- 背景
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Synonyms: SPIN, Spindlin-1, Ovarian cancer-related protein, Spindlin1, SPIN1, OCR
Background: Chromatin reader that specifically recognizes and binds histone H3 both trimethylated at 'Lys-4' and asymmetrically dimethylated at 'Arg-8' (H3K4me3 and H3R8me2a) and acts as an activator of Wnt signaling pathway dowstream of PRMT2. In case of cancer, promotes cell cancer proliferation via activation of the Wnt signaling pathway (PubMed:24589551). Overexpression induces metaphase arrest and chromosomal instability. Localizes to active rDNA loci and promotes the expression of rRNA genes (PubMed:21960006). May play a role in cell-cycle regulation during the transition from gamete to embryo. Involved in oocyte meiotic resumption, a process that takes place before ovulation to resume meiosis of oocytes blocked in prophase I: may act by regulating maternal transcripts to control meiotic resumption.
- 基因ID
- 10927
- UniProt
- Q9Y657
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