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ITGB3BP 抗体 (N-Term)

The 兔 多克隆 anti-ITGB3BP antibody is suitable to detect ITGB3BP in samples from 人 和 犬. It has been validated for WB.
产品编号 ABIN5516800
发货至: 中国
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Quick Overview for ITGB3BP 抗体 (N-Term) (ABIN5516800)

抗原

See all ITGB3BP 抗体
ITGB3BP (Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP))

适用

  • 25
  • 6
  • 5
  • 1
人, 犬

宿主

  • 23
  • 2

克隆类型

  • 23
  • 2
多克隆

标记

  • 18
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This ITGB3BP antibody is un-conjugated

应用范围

  • 15
  • 11
  • 6
  • 4
  • 1
Western Blotting (WB)
  • 抗原表位

    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    序列

    QMSLFASPTS SEEQKHRNGL SNEKRKKLNH PSLTESKEST TKDNDEFMML

    预测反应

    Dog: 91%, Human: 100%

    产品特性

    This is a rabbit polyclonal antibody against ITGB3BP. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N-terminal region of Human ITGB3BP
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    ITGB3BP (Integrin beta 3 Binding Protein (Beta3-Endonexin) (ITGB3BP))

    别名

    ITGB3BP

    背景

    This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants.

    Alias Symbols: ITGB3BP, CENPR, NRIF3,

    Protein Interaction Partner: PIH1D2, UBR7, ARFIP2, COL4A3BP, KIFC3, KDM1A, UBC, APP, CENPP, CENPO, SVIL, MAPK6, ACTN2, MTA1, ITGB3BP, DDX24, RECQL5, RXRA, ITGB3, NFKB1, ITGB5, ESR1, CCNA2, THRA, RELA, RXRG,

    Protein Size: 216

    基因ID

    23421

    NCBI登录号

    NP_055103

    途径

    Neurotrophin Signaling Pathway
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