GPR31 抗体 (C-Term)
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北京 101111
Quick Overview for GPR31 抗体 (C-Term) (ABIN5516748)
抗原
See all GPR31 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- GPR31 Antibody - C-terminal region
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序列
- QKRLREPEKQ PKLQRAQALV TLVVVLFALC FLPCFLARVL MHIFQNLGSC
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产品特性
- This is a rabbit polyclonal antibody against GPR31. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human GPR31
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP66579-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- GPR31 (G Protein-Coupled Receptor 31 (GPR31))
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别名
- GPR31
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背景
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Background Information: GPR31 is a high-affinity receptor for 12-(S)-hydroxy-5,8,10,14- eicosatetraenoic acid (12-S-HETE). 12-(S)-HETE is an arachidonic acid metabolite secreted by platelets and tumor cells, and known to induce endothelial cells retraction allowing invasive cell access to the subendothelial matrix, which is a critical step for extravasation or metastasis. Ligand-binding lead to activation of ERK1/2 (MAPK3/MAPK1), MEK, and NF-kappa-B.
Alternative Symbols: HETER, HETER1, 12-HETER
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分子量
- 35kDa
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基因ID
- 2853
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NCBI登录号
- NP_005290
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UniProt
- O00270
抗原
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