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EIF5A 抗体 (N-Term)

This anti-EIF5A antibody is a 兔 多克隆 antibody detecting EIF5A in WB. Suitable for 人, 小鼠, 大鼠, Cow, 兔, 绵羊, 犬, 豚鼠, 马 和 斑马鱼.
产品编号 ABIN5516707
发货至: 中国

Quick Overview for EIF5A 抗体 (N-Term) (ABIN5516707)

抗原

See all EIF5A 抗体
EIF5A (Eukaryotic Translation Initiation Factor 5A (EIF5A))

适用

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人, 小鼠, 大鼠, Cow, 兔, 绵羊, 犬, 豚鼠, 马, 斑马鱼

宿主

  • 40
  • 5
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  • 1

克隆类型

  • 35
  • 14
多克隆

标记

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This EIF5A antibody is un-conjugated

应用范围

  • 23
  • 15
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  • 10
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  • 2
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  • 1
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Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    LKGRPCKIVE MSTSKTGKHG HAKVHLVGID IFTGKKYEDI CPSTHNMDVP

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 93%

    产品特性

    This is a rabbit polyclonal antibody against EIF5A. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N-terminal region of Human EIF5A
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    EIF5A (Eukaryotic Translation Initiation Factor 5A (EIF5A))

    别名

    EIF5A

    背景

    EIF5A is a mRNA-binding protein involved in translation elongation. It has an important function at the level of mRNA turnover, probably acting downstream of decapping. It is involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. With syntenin SDCBP, EIF5A functions as a regulator of p53/TP53 and p53/TP53-dependent apoptosis. EIF5A regulates also TNF-alpha-mediated apoptosis and mediates effects of polyamines on neuronal process extension and survival. It may play an important role in brain development and function, and in skeletal muscle stem cell differentiation. EIF5A is also described as a cellular cofactor of human T-cell leukemia virus type I (HTLV-1) Rex protein and of human immunodeficiency virus type 1 (HIV-1) Rev protein, essential for mRNA export of retroviral transcripts.

    Protein Interaction Partner: HUWE1, UBC, REL, MEOX2, DHPS, CRX, DCP2, STUB1, BCCIP, WDR1, GDA, TYMS, PEPD, MVD, HSPD1, GNS, GLS, UBD, NPM1, IQCB1, ATF2, VCP, MACF1, DDX17, VAPA, XPO1, ATP5B, XPO4, CUL2, COPS5, TCF3, ELAVL1, SUMO2, VHL, Pds5a, Csnk1e, DOHH, XRN2, RPL5, TGM2,

    Protein Size: 184

    基因ID

    1984

    途径

    Regulation of Muscle Cell Differentiation
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