CD1c 抗体 (C-Term)
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Quick Overview for CD1c 抗体 (C-Term) (ABIN5516504)
抗原
See all CD1c (CD1C) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- ASGFYPKPVW VTWMRNEQEQ LGTKHGDILP NADGTWYLQV ILEVASEEPA
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预测反应
- Human: 100%, Rat: 86%
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产品特性
- This is a rabbit polyclonal antibody against CD1C. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human CD1C
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CD1c (CD1C) (T-cell surface glycoprotein CD1c (CD1C))
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别名
- CD1C
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背景
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This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known.
Alias Symbols: BDCA1, CD1, CD1A, R7
Protein Size: 333 -
基因ID
- 911
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NCBI登录号
- NM_001765, NP_001756
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UniProt
- P29017
抗原
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