CRBN 抗体 (Middle Region)
Quick Overview for CRBN 抗体 (Middle Region) (ABIN5516299)
抗原
See all CRBN 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- GIEIVKVKAI GRQRFKVLEL RTQSDGIQQA KVQILPECVL PSTMSAVQLE
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预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
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产品特性
- This is a rabbit polyclonal antibody against CRBN. It was validated on Western Blot.
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纯化方法
- Affinity purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of Human CRBN
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CRBN (Cereblon (CRBN))
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别名
- CRBN
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背景
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This gene encodes a protein related to the Lon protease protein family. In rodents and other mammals this gene product is found in the cytoplasm localized with a calcium channel membrane protein, and is thought to play a role in brain development. Mutations in this gene are associated with autosomal recessive nonsyndromic mental retardation. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: CRBN, AD-006,
Protein Interaction Partner: PAK7, RBPMS, MEIS2, DDB1, IKZF3, IKZF1, SUV39H1, KDM1A, UBC, COPS4, COPS6, COPS3, PSMB4, PSMA2, COPS5, CUL4A, PRKAA1, RBX1,
Protein Size: 442 -
基因ID
- 51185
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NCBI登录号
- NP_057386
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UniProt
- Q96SW2
抗原
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