Urm1 抗体 (N-Term)
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北京 101111
Quick Overview for Urm1 抗体 (N-Term) (ABIN5516189)
抗原
See all Urm1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- TLPGQEEPWD IRNLLIWIKK NLLKERPELF IQGDSVRPGI LVLINDADWE
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产品特性
- This is a rabbit polyclonal antibody against URM1. It was validated on Western Blot.
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纯化方法
- Affinity purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human URM1
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anti-Ubiquitin Related Modifier 1 (Urm1) (AA 1-63) antibody
Urm1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Related Modifier 1 (Urm1) antibodyUrm1 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Related Modifier 1 (Urm1) (Internal Region) antibodyUrm1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Related Modifier 1 (Urm1) antibodyUrm1 适用: Saccharomyces cerevisiae WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Urm1 (Ubiquitin Related Modifier 1 (Urm1))
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别名
- URM1
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背景
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URM1 acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). URM1 serves as sulfur donor in tRNA 2- thiolation reaction by being thiocarboxylated (-COSH) at its C- terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such as MOCS3, ATPBD3, CTU2, USP15 and CAS. The thiocarboxylated form serves as substrate for conjugation and oxidative stress specifically induces the formation of UBL-protein conjugates.
Alias Symbols: C9orf74
Protein Interaction Partner: SEC23IP, DSTN, PTGES3, TXNL1, USP5, XPO1, VCL, PRDX2, PRDX1, ATP6V1A, CTU1, UBC, ASCC2, TBL3, CDK11B, UBA4,
Protein Size: 101 -
基因ID
- 81605
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NCBI登录号
- NP_112176
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UniProt
- Q9BTM9
抗原
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