INCENP 抗体 (C-Term)
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Quick Overview for INCENP 抗体 (C-Term) (ABIN5516066)
抗原
See all INCENP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- RELEEKKKKE EQQRLAERQL QEEQEKKAKE AAGASKALNV TVDVQSPACT
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预测反应
- Horse: 85%, Human: 100%, Mouse: 86%, Pig: 92%, Rabbit: 92%, Rat: 86%
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产品特性
- This is a rabbit polyclonal antibody against INCENP. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human INCENP
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- INCENP (Inner Centromere Protein Antigens 135/155kDa (INCENP))
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别名
- INCENP
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背景
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In mammalian cells, 2 broad groups of centromere-interacting proteins have been described: constitutively binding centromere proteins and 'passenger,' or transiently interacting, proteins (reviewed by Choo, 1997). The constitutive proteins include CENPA, CENPB, CENPC1, and CENPD. The term 'passenger proteins' encompasses a broad collection of proteins that localize to the centromere during specific stages of the cell cycle. These include CENPE, MCAK, KID, cytoplasmic dynein, CliPs, and CENPF/mitosin. The inner centromere proteins (INCENPs), the initial members of the passenger protein group, display a broad localization along chromosomes in the early stages of mitosis but gradually become concentrated at centromeres as the cell cycle progresses into mid-metaphase. During telophase, the proteins are located within the midbody in the intercellular bridge, where they are discarded after cytokinesis
Alias Symbols: INCENP,
Protein Interaction Partner: FLOT1, AURKB, HECW2, AURKC, AURKA, UBC, CDCA8, BIRC5, CBX5, HIST2H3C, SIRT7, Incenp, TUBA1A, EVI5, H2AFZ, SGOL1,
Protein Size: 918 -
基因ID
- 3619
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NCBI登录号
- NP_064623
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UniProt
- Q9NQS7
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途径
- Cell Division Cycle
抗原
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