APEX2 抗体 (C-Term)
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北京 101111
Quick Overview for APEX2 抗体 (C-Term) (ABIN5515372)
抗原
See all APEX2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- APEX2 Antibody - C-terminal region
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序列
- LMTPKTPEEK AVAKVVKGQA KTSEAKDEKE LRTSFWKSVL AGPLRTPLCG
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预测反应
- Cow: 85%, Horse: 93%, Human: 100%, Rat: 77%
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纯化方法
- Affinity purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human APEX2
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anti-APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2) (AA 143-171) antibody
APEX2 适用: 人 WB, FACS, IF, IHC (p) 宿主: 兔 Polyclonal RB23043 unconjugated
anti-APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2) (AA 1-518) antibodyAPEX2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2) (AA 102-210) antibodyAPEX2 适用: 人, 猴, 小鼠, 大鼠 WB, FACS 宿主: 兔 Polyclonal unconjugated
anti-APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2) (AA 301-400) antibodyAPEX2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2) antibodyAPEX2 适用: 人 WB, FACS, IHC, IF/ICC 宿主: 兔 Polyclonal unconjugated
anti-APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2) (AA 1-500) antibodyAPEX2 适用: 人 WB, FACS, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP65215-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- APEX2 (APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2))
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别名
- APEX2
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背景
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Background Information: Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes a protein shown to have a weak class II AP endonuclease activity. Most of the encoded protein is located in the nucleus but some is also present in mitochondria. This protein may play an important role in both nuclear and mitochondrial base excision repair. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene Name: apurinic/apyrimidinic endodeoxyribonuclease 2
Alternative Symbols: APE2, XTH2, ZGRF2, APEXL2
Protein Name: DNA-(apurinic or apyrimidinic site) lyase 2
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分子量
- 57 kDa
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基因ID
- 27301
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NCBI登录号
- NP_055296
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UniProt
- Q9UBZ4
抗原
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