IL-7 抗体 (C-Term)
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北京 101111
Quick Overview for IL-7 抗体 (C-Term) (ABIN5514877)
抗原
See all IL-7 (IL7) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- LKVSEGTTIL LNCTGQVKGR KPAALGEAQP TKSLEENKSL KEQKKLNDLC
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预测反应
- Cow: 86%, Dog: 86%, Horse: 93%, Human: 100%, Pig: 100%, Sheep: 93%, Yeast: 85%
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产品特性
- This is a rabbit polyclonal antibody against IL7. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human IL7
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- IL-7 (IL7) (Interleukin 7 (IL7))
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别名
- IL7
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背景
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The protein encoded by this gene is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their presence in normal tissues has not been confirmed.
Alias Symbols: IL7,
Protein Interaction Partner: CEBPE, APP, IL2RG, IL7R,
Protein Size: 177 -
基因ID
- 3574
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UniProt
- P13232
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途径
- JAK/STAT Signaling
抗原
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