Histone H3.3 抗体 (N-Term)
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Quick Overview for Histone H3.3 抗体 (N-Term) (ABIN5514837)
抗原
See all Histone H3.3 (H3F3A) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- RTKQTARKST GGKAPRKQLA TKAARKSAPS TGGVKKPHRY RPGTVALREI
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产品特性
- This is a rabbit polyclonal antibody against H3F3A. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human H3F3A
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Histone H3.3 (H3F3A) (H3 Histone, Family 3A (H3F3A))
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别名
- H3F3A
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背景
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Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene contains introns and its mRNA is polyadenylated, unlike most histone genes. The protein encoded is a replication-independent member of the histone H3 family.
Alias Symbols: H3F3A, H3.3B,
Protein Interaction Partner: FUS, DAXX, CENPA, ATRX, ZMYND11, HIST1H4A, UBC, PML, H2AFY, UHRF1, ASB9, ASB16, ASB2, RNF2, CORO1C, PUF60, NUDC, VPS26A, SNX2, PAWR, VPS35, VPS29, FAM129B, SNX6, ASF1B, ASF1A, HIRA, CHAF1A, ITGA4, HIST4H4, NOS3, LRRK2, HIST1H4F, KDM4A, SSRP1, BRD1, EFS, S
Protein Size: 136 -
基因ID
- 3020
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NCBI登录号
- NP_005315
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UniProt
- P84243
抗原
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