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GAD65 抗体 (N-Term)

GAD2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5514805
发货至: 中国
  • 抗原 See all GAD65 (GAD2) 抗体
    GAD65 (GAD2) (Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2))
    抗原表位
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    N-Term
    适用
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    宿主
    • 91
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    克隆类型
    • 94
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    多克隆
    标记
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    This GAD65 antibody is un-conjugated
    应用范围
    • 99
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    Western Blotting (WB)
    序列
    FGSEDGSGDS ENPGTARAWC QVAQKFTGGI GNKLCALLYG DAEKPAESGG
    产品特性
    This is a rabbit polyclonal antibody against DCE2. It was validated on Western Blot.
    纯化方法
    Affinity purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N-terminal region of Human DCE2
    Top Product
    Discover our top product GAD2 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    GAD65 (GAD2) (Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2))
    别名
    DCE2 (GAD2 产品)
    别名
    GAD65 antibody, gad65 antibody, F12P19.12 antibody, F12P19_12 antibody, GLUTAMATE DECARBOXYLASE 2 antibody, glutamate decarboxylase 2 antibody, zgc:112198 antibody, 6330404F12Rik antibody, GAD(65) antibody, Gad-2 antibody, glutamate decarboxylase 2 antibody, glutamate decarboxylase 1 antibody, glutamic acid decarboxylase 2 antibody, GAD2 antibody, PTRG_06148 antibody, LOC9324534 antibody, Gad2 antibody, GAD1 antibody, gad2 antibody
    背景
    This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.

    Alias Symbols: GAD2, GAD65,

    Protein Interaction Partner: CMTM5, MAL2, TMEM159, AGTRAP, ARL6IP1, GAD1, F10, PRKCE, PRKACA, ZDHHC17,

    Protein Size: 585
    基因ID
    2572
    NCBI登录号
    NP_001127838
    UniProt
    Q05329
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