GAD65 抗体 (N-Term)
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Quick Overview for GAD65 抗体 (N-Term) (ABIN5514805)
抗原
See all GAD65 (GAD2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- FGSEDGSGDS ENPGTARAWC QVAQKFTGGI GNKLCALLYG DAEKPAESGG
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产品特性
- This is a rabbit polyclonal antibody against DCE2. It was validated on Western Blot.
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纯化方法
- Affinity purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human DCE2
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- GAD65 (GAD2) (Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2))
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别名
- DCE2
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背景
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This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.
Alias Symbols: GAD2, GAD65,
Protein Interaction Partner: CMTM5, MAL2, TMEM159, AGTRAP, ARL6IP1, GAD1, F10, PRKCE, PRKACA, ZDHHC17,
Protein Size: 585 -
基因ID
- 2572
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NCBI登录号
- NP_001127838
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UniProt
- Q05329
抗原
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