Complement Factor I 抗体 (C-Term)
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- 抗原 See all Complement Factor I (CFI) 抗体
- Complement Factor I (CFI)
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抗原表位
- C-Term
- 适用
- 人, 小鼠, 大鼠, 犬, 豚鼠, 马, Pig, 兔, Cow
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Complement Factor I antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- AGTYDGSIDA CKGDSGGPLV CMDANNVTYV WGVVSWGENC GKPEFPGVYT
- 预测反应
- Cow: 77%, Dog: 77%, Guinea Pig: 79%, Horse: 83%, Human: 100%, Mouse: 86%, Pig: 85%, Rabbit: 83%, Rat: 86%
- 产品特性
- This is a rabbit polyclonal antibody against CFI. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human CFI
- Top Product
- Discover our top product CFI Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- Complement Factor I (CFI)
- 别名
- CFI (CFI 产品)
- 别名
- cfi antibody, MGC53615 antibody, Cfi antibody, factor I antibody, IF antibody, gb:ai721528 antibody, ahus3 antibody, c3b-ina antibody, c3bc4bi antibody, c3bina antibody, kaf antibody, CFI antibody, AHUS3 antibody, C3BINA antibody, C3b-INA antibody, FI antibody, KAF antibody, complement factor I S homeolog antibody, complement factor I L homeolog antibody, complement factor I antibody, complement component factor i antibody, cfi.S antibody, cfi.L antibody, CFI antibody, cfi antibody, Cfi antibody
- 背景
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This gene encodes a serine proteinase that is essential for regulating the complement cascade. The encoded preproprotein is cleaved to produce both heavy and light chains, which are linked by disulfide bonds to form a heterodimeric glycoprotein. This heterodimer can cleave and inactivate the complement components C4b and C3b, and it prevents the assembly of the C3 and C5 convertase enzymes. Defects in this gene cause complement factor I deficiency, an autosomal recessive disease associated with a susceptibility to pyogenic infections. Mutations in this gene have been associated with a predisposition to atypical hemolytic uraemic syndrome, a disease characterized by acute renal failure, microangiopathic hemolytic anemia and thrombocytopenia. Primary glomerulonephritis with immmune deposits is another condition associated with mutation of this gene.
Alias Symbols: CFI, IF,
Protein Interaction Partner: GLP1R, CFH, C3,
Protein Size: 583 - 基因ID
- 3426
- NCBI登录号
- NM_000204, NP_000195
- UniProt
- P05156
- 途径
- Complement System
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