Complement Factor I 抗体 (C-Term)
Quick Overview for Complement Factor I 抗体 (C-Term) (ABIN5514688)
抗原
See all Complement Factor I (CFI) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- AGTYDGSIDA CKGDSGGPLV CMDANNVTYV WGVVSWGENC GKPEFPGVYT
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预测反应
- Cow: 77%, Dog: 77%, Guinea Pig: 79%, Horse: 83%, Human: 100%, Mouse: 86%, Pig: 85%, Rabbit: 83%, Rat: 86%
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产品特性
- This is a rabbit polyclonal antibody against CFI. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human CFI
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anti-Complement Factor I (CFI) (AA 28-243) antibody
CFI 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor I (CFI) (AA 358-603) antibodyCFI 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor I (CFI) (AA 19-118) antibodyCFI 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1B3 unconjugated
anti-Complement Factor I (CFI) (AA 239-316) antibodyCFI 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor I (CFI) (AA 1-377) antibodyCFI 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Complement Factor I (CFI) (AA 340-583) antibodyCFI 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor I (CFI) (AA 19-118) antibodyCFI 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Complement Factor I (CFI) (AA 145-194) antibodyCFI 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor I (CFI) (AA 1-377) antibodyCFI 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor I (CFI) (AA 19-300) antibodyCFI 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Complement Factor I (CFI)
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别名
- CFI
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背景
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This gene encodes a serine proteinase that is essential for regulating the complement cascade. The encoded preproprotein is cleaved to produce both heavy and light chains, which are linked by disulfide bonds to form a heterodimeric glycoprotein. This heterodimer can cleave and inactivate the complement components C4b and C3b, and it prevents the assembly of the C3 and C5 convertase enzymes. Defects in this gene cause complement factor I deficiency, an autosomal recessive disease associated with a susceptibility to pyogenic infections. Mutations in this gene have been associated with a predisposition to atypical hemolytic uraemic syndrome, a disease characterized by acute renal failure, microangiopathic hemolytic anemia and thrombocytopenia. Primary glomerulonephritis with immmune deposits is another condition associated with mutation of this gene.
Alias Symbols: CFI, IF,
Protein Interaction Partner: GLP1R, CFH, C3,
Protein Size: 583 -
基因ID
- 3426
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NCBI登录号
- NM_000204, NP_000195
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UniProt
- P05156
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途径
- Complement System
抗原
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