Complement Factor B 抗体 (N-Term)
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北京 101111
Quick Overview for Complement Factor B 抗体 (N-Term) (ABIN5514558)
抗原
See all Complement Factor B (CFB) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- CFB Antibody - N-terminal region
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序列
- NGAGYCSNPG IPIGTRKVGS QYRLEDSVTY HCSRGLTLRG SQRRTCQEGG
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预测反应
- Cow: 93%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Sheep: 93%
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产品特性
- This is a rabbit polyclonal antibody against CFAB. It was validated on Western Blot.
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纯化方法
- Affinity purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human CFAB
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anti-Complement Factor B (CFB) antibody
CFB 适用: 人, 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor B (CFB) (AA 474-590) antibodyCFB 适用: 小鼠 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor B (CFB) (AA 34-159) antibodyCFB 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor B (CFB) antibodyCFB 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor B (CFB) (AA 469-494) antibodyCFB 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB21500 unconjugated
anti-Complement Factor B (CFB) (AA 26-751) antibodyCFB 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor B (CFB) antibodyCFB 适用: 人 IHC (p), ID 宿主: 山羊 Polyclonal unconjugated
anti-Complement Factor B (CFB) (AA 301-400) antibodyCFB 适用: 人 WB, IHC (p), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor B (CFB) (AA 35-160) antibodyCFB 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor B (CFB) (AA 32-157) antibodyCFB 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP56331-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- Complement Factor B (CFB)
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别名
- CFB
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背景
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Background Information: This gene encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. This cluster includes several genes involved in regulation of the immune reaction. Polymorphisms in this gene are associated with a reduced risk of age-related macular degeneration. The polyadenylation site of this gene is 421 bp from the 5' end of the gene for complement component 2.
Gene Name: complement factor B
Alternative Symbols: BF, FB, BFD, GBG, CFAB, CFBD, PBF2, AHUS4, FBI12, H2-Bf, ARMD14
Protein Name: complement factor B
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分子量
- 84kDa
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基因ID
- 629
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NCBI登录号
- NP_001701
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UniProt
- P00751
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途径
- Complement System, Proton Transport, Ribonucleoside Biosynthetic Process
抗原
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