HLA-DOA 抗体 (N-Term)
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北京 101111
Quick Overview for HLA-DOA 抗体 (N-Term) (ABIN5514394)
抗原
See all HLA-DOA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- HLA-DOA Antibody - N-terminal region
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序列
- LMTLLSPQEA GATKADHMGS YGPAFYQSYG ASGQFTHEFD EEQLFSVDLK
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预测反应
- Cow: 83%, Horse: 85%, Human: 100%, Pig: 86%, Rat: 79%
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产品特性
- This is a rabbit polyclonal antibody against DOA. It was validated on Western Blot.
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纯化方法
- Affinity purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human DOA
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP65329-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- HLA-DOA (HLA Class II DO alpha (HLA-DOA))
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别名
- HLA-DOA
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背景
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Background Information: HLA-DOA belongs to the HLA class II alpha chain paralogues. HLA-DOA forms a heterodimer with HLA-DOB. The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level.
Gene Name: major histocompatibility complex, class II, DO alpha
Alternative Symbols: HLADZ, HLA-DNA, HLA-DZA
Protein Name: HLA class II histocompatibility antigen, DO alpha chain
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分子量
- 27kDa
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基因ID
- 3111
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NCBI登录号
- NP_002110
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UniProt
- P06340
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途径
- Human Leukocyte Antigen (HLA) in Adaptive Immune Response
抗原
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