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HLA-DOA 抗体 (N-Term)

The 兔 多克隆 anti-HLA-DOA antibody is suitable to detect HLA-DOA in samples from 人, 大鼠, Cow, 马 和 Pig. It has been validated for WB.
产品编号 ABIN5514394
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for HLA-DOA 抗体 (N-Term) (ABIN5514394)

抗原

See all HLA-DOA 抗体
HLA-DOA (HLA Class II DO alpha (HLA-DOA))

适用

人, 大鼠, Cow, 马, Pig

宿主

  • 17
  • 2
兔

克隆类型

  • 19
多克隆

标记

  • 12
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This HLA-DOA antibody is un-conjugated

应用范围

  • 11
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    N-Term

    原理

    HLA-DOA Antibody - N-terminal region

    序列

    LMTLLSPQEA GATKADHMGS YGPAFYQSYG ASGQFTHEFD EEQLFSVDLK

    预测反应

    Cow: 83%, Horse: 85%, Human: 100%, Pig: 86%, Rat: 79%

    产品特性

    This is a rabbit polyclonal antibody against DOA. It was validated on Western Blot.

    纯化方法

    Affinity purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N-terminal region of Human DOA
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP65329-100UG

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    prevent freeze-thaw cycles

    储存条件

    4 °C,-20 °C

    储存方法

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    HLA-DOA (HLA Class II DO alpha (HLA-DOA))

    别名

    HLA-DOA

    背景

    Background Information: HLA-DOA belongs to the HLA class II alpha chain paralogues. HLA-DOA forms a heterodimer with HLA-DOB. The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level.

    Gene Name: major histocompatibility complex, class II, DO alpha

    Alternative Symbols: HLADZ, HLA-DNA, HLA-DZA

    Protein Name: HLA class II histocompatibility antigen, DO alpha chain

    分子量

    27kDa

    基因ID

    3111

    NCBI登录号

    NP_002110

    UniProt

    P06340

    途径

    Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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