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Bystin 抗体 (N-Term)

BYST 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5514386
发货至: 中国
  • 抗原 See all Bystin (BYST) products
    Bystin (BYST)
    抗原表位
    • 1
    • 1
    N-Term
    适用
    宿主
    • 3
    克隆类型
    • 3
    多克隆
    标记
    • 3
    This Bystin antibody is un-conjugated
    应用范围
    • 2
    • 1
    • 1
    Western Blotting (WB)
    序列
    RGTGEAEEEY VGPRLSRRIL QQARQQQEEL EAEHGTGDKP AAPRERTTRL
    产品特性
    This is a rabbit polyclonal antibody against BYST. It was validated on Western Blot.
    纯化方法
    Affinity purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N-terminal region of Human BYST
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    Bystin (BYST)
    别名
    BYST (BYST 产品)
    背景
    Bystin is expressed as a 2-kb major transcript and a 3.6-kb minor transcript in SNG-M cells and in human trophoblastic teratocarcinoma HT-H cells. Protein binding assays determined that bystin binds directly to trophinin and tastin, and that binding is enhanced when cytokeratins 8 and 18 are present. Immunocytochemistry of HT-H cells showed that bystin colocalizes with trophinin, tastin, and the cytokeratins, suggesting that these molecules form a complex in trophectoderm cells at the time of implantation. Using immunohistochemistry it was determined that trophinin and bystin are found in the placenta from the sixth week of pregnancy. Both proteins were localized in the cytoplasm of the syncytiotrophoblast in the chorionic villi and in endometrial decidual cells at the uteroplacental interface. After week 10, the levels of trophinin, tastin, and bystin decreased and then disappeared from placental villi.

    Alias Symbols: BYSL,

    Protein Interaction Partner: ZBTB8A, KRTAP10-3, KRTAP10-5, SMN2, TRIM27, TRIM37, MID1, GOLGA2, EPS8, EMD, PHC2, AES, KRTAP10-7, CEP57L1, BEND7, FAM9B, OLIG3, MIPOL1, RALYL, KRT40, SSX2IP, MRFAP1L1, LONRF1, KRTAP4-2, C1orf94, LTV1, L3MBTL3, LZTS2, TEKT1, DOCK8, CEP44, CEP70, CCDC33, C

    Protein Size: 437
    基因ID
    705
    NCBI登录号
    NP_004044
    UniProt
    Q13895
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