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RNF111 抗体 (AA 1-108)

Cited in 9+ publications. This 小鼠 单克隆 anti-RNF111 antibody (Clone 1C4) specifically detects RNF111 in WB, ELISA, IF 和 RNAi. The antibody is reactive with 人 samples.
产品编号 ABIN527194
发货至: 中国
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中国
北京 101111
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for RNF111 抗体 (AA 1-108) (ABIN527194)

抗原

See all RNF111 抗体
RNF111 (Ring Finger Protein 111 (RNF111))

适用

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宿主

  • 46
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小鼠

克隆类型

  • 48
  • 1
单克隆

标记

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This RNF111 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), RNA Interference (RNAi)

克隆位点

1C4
  • 抗原表位

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    AA 1-108

    原理

    Mouse monoclonal antibody raised against a partial recombinant RNF111.

    序列

    MSQWTPEYNE LYTLKVDMKS EIPSDAPKTQ ESLKGILLHP EPIGAAKSFP AGVEMINSKV GNEFSHLCDD SQKQEKEMNG NQQEQEKSLV VRKKRKSQQA GPSYVQNC

    交叉反应

    产品特性

    Antibody Reactive Against Recombinant Protein.

    免疫原

    RNF111 (NP_060080, 1 a.a. ~ 108 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

    亚型

    IgG2a
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    In 1x PBS, pH 7.4

    注意事项

    Aliquot to avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • van Cuijk, van Belle, Turkyilmaz, Poulsen, Janssens, Theil, Sabatella, Lans, Mailand, Houtsmuller, Vermeulen, Marteijn: "SUMO and ubiquitin-dependent XPC exchange drives nucleotide excision repair." in: Nature communications, Vol. 6, pp. 7499, (2015) (PubMed).

    Ma, Chen, Zhang, Yang, Wang, Yu: "RNF111-dependent neddylation activates DNA damage-induced ubiquitination." in: Molecular cell, Vol. 49, Issue 5, pp. 897-907, (2013) (PubMed).

    Erker, Neyret-Kahn, Seeler, Dejean, Atfi, Levy: "Arkadia, a novel SUMO-targeted ubiquitin ligase involved in PML degradation." in: Molecular and cellular biology, Vol. 33, Issue 11, pp. 2163-77, (2013) (PubMed).

    Poulsen, Hansen, Wagner, van Cuijk, van Belle, Streicher, Wikström, Choudhary, Houtsmuller, Marteijn, Bekker-Jensen, Mailand: "RNF111/Arkadia is a SUMO-targeted ubiquitin ligase that facilitates the DNA damage response." in: The Journal of cell biology, Vol. 201, Issue 6, pp. 797-807, (2013) (PubMed).

    Javelaud, van Kempen, Alexaki, Le Scolan, Luo, Mauviel: "Efficient TGF-?/SMAD signaling in human melanoma cells associated with high c-SKI/SnoN expression." in: Molecular cancer, Vol. 10, Issue 1, pp. 2, (2011) (PubMed).

    Koinuma, Shinozaki, Nagano, Ikushima, Horiguchi, Goto, Chano, Saitoh, Imamura, Miyazono, Miyazawa: "RB1CC1 protein positively regulates transforming growth factor-beta signaling through the modulation of Arkadia E3 ubiquitin ligase activity." in: The Journal of biological chemistry, Vol. 286, Issue 37, pp. 32502-12, (2011) (PubMed).

    Nagano, Koinuma, Miyazawa, Miyazono: "Context-dependent regulation of the expression of c-Ski protein by Arkadia in human cancer cells." in: Journal of biochemistry, Vol. 147, Issue 4, pp. 545-54, (2010) (PubMed).

    Nanjundan, Cheng, Zhang, Lahad, Kuo, Schmandt, Smith-McCune, Fishman, Gray, Mills: "Overexpression of SnoN/SkiL, amplified at the 3q26.2 locus, in ovarian cancers: a role in ovarian pathogenesis." in: Molecular oncology, Vol. 2, Issue 2, pp. 164-81, (2009) (PubMed).

    Levy, Howell, Das, Harkin, Episkopou, Hill: "Arkadia activates Smad3/Smad4-dependent transcription by triggering signal-induced SnoN degradation." in: Molecular and cellular biology, Vol. 27, Issue 17, pp. 6068-83, (2007) (PubMed).

  • 抗原

    RNF111 (Ring Finger Protein 111 (RNF111))

    别名

    RNF111

    背景

    Full Gene Name: ring finger protein 111
    Synonyms: ARK,DKFZp313E0731,DKFZp686H1966,DKFZp761D081,FLJ38008

    基因ID

    54778

    NCBI登录号

    NM_017610
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